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Case Reports
. 2021 Jul 21;14(7):e241154.
doi: 10.1136/bcr-2020-241154.

Omani experience with the use of factor IX Fc fusion protein

Affiliations
Case Reports

Omani experience with the use of factor IX Fc fusion protein

Shireen I Alzadjali et al. BMJ Case Rep. .

Abstract

We describe our local experience in the management of haemophilia B patients with factor IX Fc fusion protein. Two children with haemophilia B were managed with the use of a personalised/tailored dosing schedule of factor IX Fc fusion protein. Compared with the standard half-life factor IX, prophylaxis with factor IX Fc fusion protein was cost-effective, with much less injections, better bleeding control, improved tolerability or no inhibitor development.

Keywords: congenital disorders; haematology (incl blood transfusion); paediatrics.

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Conflict of interest statement

Competing interests: None declared.

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References

    1. National Hemophila Foundation . Bleeding disorder, types of bleeding disorder (hemophilia B), 2019. Available: https://www.hemophilia.org/Bleeding-Disorders/Types-of-Bleeding-Disorder...
    1. Srivastava A, Brewer AK, Mauser-Bunschoten EP, et al. . Guidelines for the management of hemophilia. Haemophilia 2013;19:e1–47. 10.1111/j.1365-2516.2012.02909.x - DOI - PubMed
    1. Mannucci PM. Hemophilia therapy: the future has begun. Haematologica 2020;105:545–53. 10.3324/haematol.2019.232132 - DOI - PMC - PubMed
    1. Taylor JA, Kruse-Jarres R. A new era for hemophilia B treatment. Blood 2016;127:1734–6. 10.1182/blood-2016-02-694869 - DOI - PMC - PubMed
    1. Graf L. Extended half-life factor VIII and factor IX preparations. Transfus Med Hemother 2018;45:86–91. 10.1159/000488060 - DOI - PMC - PubMed

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