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. 2021 Aug;20(8):1027-1032.
doi: 10.1007/s43630-021-00077-z. Epub 2021 Jul 22.

Latex membranes with methylene blue dye for antimicrobial photodynamic therapy

Maria Andrelina O Sousa  1 , Marco A C de Faria  1 , Rita P Ribeiro  1 , João V P Valverde  1 , Herica D Rocha  1 , Kevin F Dos Santos  1 , Marcos S Sousa  1 , Paula C S Souto  1 , Josmary R Silva  1 , Nara C de Souza  2
Affiliations

Latex membranes with methylene blue dye for antimicrobial photodynamic therapy

Maria Andrelina O Sousa et al. Photochem Photobiol Sci. 2021 Aug.

Abstract

The search for new materials that can be applied in the treatment of injured human tissues has led to the development of new dressings. Membranes have potential as dressing materials because they can be fitted to and interact with the tissue surface. In this study, we analyze the morphological properties and wettability of latex membranes, along with the incorporation of the photosensitizer methylene blue, in the context of the utility of the membranes in curative applications involving photodynamic therapy (PDT). It was observed that deposition of the photosensitizer into latex membranes increased both the surface roughness and wettability. Antifungal testing indicated that antimicrobial PDT assisted by the latex membranes incorporating methylene blue effectively inactivated Candida albicans.

Keywords: Burn; Microscopy; Natural rubber; Wettability.

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References

    1. Burn prevention: success stories and lessons learned - World Health Organization - March 2011 (ISBN 978 92 4 150118 7). https://www.who.int/publications/i/item/9789241501187
    1. Khoo, T. L., Halim, A. S., Saad, A. Z. M., & Dorai, A. A. (2010). The application of glycerol-preserved skin allograft in the treatment of burn injuries: An analysis based on indications. Burns, 36, 897–904. https://doi.org/10.1016/j.burns.2009.03.007 - DOI - PubMed
    1. Church, D., Elsayed, S., Reid, O., Winston, B., & Lindsay, R. (2006). Burn wound infections. Clinical Microbiology Reviews, 19, 403–434. https://doi.org/10.1128/CMR.19.2.403-434.2006 - DOI - PubMed - PMC
    1. Wasiak, J., Cleland, H., & Campbell, F. (2008). Dressings for superficial and partial thickness burns. In J. Wasiak (Ed.), Cochrane database systematic reviews. Chichester: Wiley. https://doi.org/10.1002/14651858.CD002106.pub3 - DOI
    1. Wattanakaroon, W., Akanitkul, P., Kaowkanya, W., & Phoudee, W. (2017). Albumin-natural rubber latex composite as a dermal wound dressing. Materials Today: Proceedings, 4, 6633–6640. https://doi.org/10.1016/j.matpr.2017.06.178 - DOI

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