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Observational Study
. 2021 Jul 22;21(1):366.
doi: 10.1186/s12903-021-01729-3.

Clinical changes in the severity of dental fluorosis: a longitudinal evaluation

Alexandra Saldarriaga  1   2 , Diego F Rojas-Gualdrón  3 , Manuel Restrepo  1 , Diego Girotto Bussaneli  1 , Camila Fragelli  1 , Rita de Cássia Loiola Cordeiro  1 , Lourdes Santos-Pinto  1 , Fabiano Jeremias  4
Affiliations
Observational Study

Clinical changes in the severity of dental fluorosis: a longitudinal evaluation

Alexandra Saldarriaga et al. BMC Oral Health. .

Abstract

Background: Dental fluorosis (DF) has been one of the most prevalent pediatric dental conditions associated with aesthetic concern and treatment needs. This study aimed to identify the longitudinal clinical change in the severity of DF in 8-12-year-old children and its association with gender, age, severity, and tooth type.

Methods: This observational study assessed the dental aspects of the 92 Colombian children in 2015 (mean age at beginning 9.71 years ± 1.23) and 2018 (mean age 13.69 years ± 1.41), from an area with high DF prevalence. DF was recorded in all permanent teeth by two calibrated examiners using the Thylstrup and Fejerskov Index (TFI). DF severity change (maximum-TFI-score) was analyzed with descriptive analysis at the tooth level. Associated factors were evaluated with the generalized linear model, binomial family, and logarithmic link function.

Results: TFI scores ranged between 1 (very mild) to 6 (severe), being score 2 (41.7%) the most prevalent. After three years, 29.6% of the teeth presented score reduction, 24.1%, increased and 46.3% did not change; the significant association was related to increasing of the basal TFI = 1 score (44.2%) (RR = 9.7; 95% CI 1.7-56.5; p = 0.01) and with canines, premolars and second-permanent-molars teeth group (RR = 3.3; 95% CI 1.9-5.6; p = 0.005).

Conclusion: The present study based on clinical features about DF confirms the dynamic post-eruptive nature of this condition. After three years of follow-up, a considerable proportion of the teeth changed to a higher score. Furthermore, the canines, premolars, and second-permanent-molars showed a higher incidence of an increase in severity of TFI score.

Keywords: Dental fluorosis; Longitudinal; Permanent dentition; Severity.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Study flow diagram
Fig. 2
Fig. 2
Distribution of TFI scores by tooth at first evaluation
Fig. 3
Fig. 3
Distribution of TFI score change by tooth after three years
See this image and copyright information in PMC

References

    1. Fejerskov O, Manji F, Baelum V. The nature and mechanisms of dental fluorosis in man. J Dent Res. 1990;69:692–700. doi: 10.1177/00220345900690S135. - DOI - PubMed
    1. Hong L, Levy SM, Broffitt B, Warren JJ, Kanellis MJ, Wefel JS, Dawson DV. Timing of fluoride intake in relation to development of fluorosis on maxillary central incisors. Community Dent Oral Epidemiol. 2006;34:299–309. doi: 10.1111/j.1600-0528.2006.00281.x. - DOI - PubMed
    1. Evans RW, Darvell BW. Refining the estimate of the critical period for susceptibility to enamel fluorosis in human maxillary central incisors. J Public Health Dent. 1995;55(4):238–249. doi: 10.1111/j.1752-7325.1995.tb02376.x. - DOI - PubMed
    1. Den Besten P, Li W. Chronic fluoride toxicity: dental fluorosis. Monogr Oral Sci. 2011;22(1):81–96. doi: 10.1159/000327028. - DOI - PMC - PubMed
    1. Bhagavatula P, Levy SM, Broffitt B, Weber-Gasparoni K, Warren JJ. Timing of fluoride intake and dental fluorosis on late-erupting permanent teeth. Community Dent Oral Epidemiol. 2016;44(1):32–45. doi: 10.1111/cdoe.12187. - DOI - PMC - PubMed

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