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. 1978 Jan;56(3):245-8.
doi: 10.1016/0027-5107(78)90191-4.

Mutagenic effect of dichloromethane on Salmonella typhimurium

W M Jongen, G M Alink, J H Koeman

Mutagenic effect of dichloromethane on Salmonella typhimurium

W M Jongen et al. Mutat Res. 1978 Jan.

Abstract

The possible mutagenicity of the organic solvent dichloromethane was investigated with the mutation test as described by Ames et al. The compound was mutagenic in both tester strains used, namely TA98 and TA100. The administration of rat-liver homogenate did not appear to be essential though it slightly increased the number of mutations.

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