Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Jun;10(6):2500-2511.
doi: 10.21037/tau-21-13.

Sexual dysfunction due to pudendal neuralgia: a systematic review

Affiliations
Review

Sexual dysfunction due to pudendal neuralgia: a systematic review

Fouad Aoun et al. Transl Androl Urol. 2021 Jun.

Abstract

Background: The pudendal nerve is considered as the main nerve of sexuality. Pudendal neuralgia is an underdiagnosed disease in clinical practice. The aim of this systematic review is to highlight the role of pudendal neuralgia on sexual dysfunction in both sexes.

Methods: A PubMed search was performed using the following keywords: "Pudendal" AND "Sexual dysfunction" or "Erectile dysfunction" or "Ejaculation" or "Persistent sexual arousal" or "Dyspareunia" or "Vulvodynia". The search involved patients having sexual dysfunction due to pudendal neuralgia. Treatment received was also reported.

Results: Five case series, seven cohort studies, two pilot studies, and three randomized clinical trials were included in this systematic review. Pudendal nerve and/or artery entrapment, or pudendal neuralgia, is a reversible cause of multiple sexual dysfunctions. Interventions such as anesthetic injections, neurolysis, and decompression are reported as potential treatment modalities. There are no studies describing the role of pudendal canal syndrome in the pathophysiology or treatment of delayed ejaculation or penile shortening.

Discussion: Pudendal neuralgia is an underestimated yet important cause of persistent genital arousal, erectile dysfunction (ED), premature ejaculation (PE), ejaculation pain, and vulvodynia. Physicians should be aware of this entity and examine the pudendal canal in such patients before concluding an idiopathic cause of sexual dysfunction.

Keywords: Pudendal nerve; ejaculation; erectile dysfunction (ED); sexual dysfunction; sexuality.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/tau-21-13). The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
PRISMA flow chart of the study.

Comment in

References

    1. Mulcahy JJ, Rehman J, Melman A. Normal Anatomy and Physiology. Male Sex Funct 2003;1-46.
    1. Masters WH, Johnson VE. The human female: anatomy of sexual response. Minn Med 1960;43:31-6. - PubMed
    1. Vignozzi L. Female sexuality: A state of mind. In: Female Sexual Function and Dysfunction. Springer International Publishing, 2017:27-32.
    1. Khonsary S. Guyton and Hall: Textbook of Medical Physiology. Vol. 8, Surgical Neurology International. 2017. 275 p.
    1. Balasubramanian A, Yu J, Breyer BN, et al. The Association Between Pelvic Discomfort and Erectile Dysfunction in Adult Male Bicyclists. J Sex Med 2020;17:919-29. 10.1016/j.jsxm.2020.01.022 - DOI - PubMed