Sexual dysfunction due to pudendal neuralgia: a systematic review
- PMID: 34295736
- PMCID: PMC8261452
- DOI: 10.21037/tau-21-13
Sexual dysfunction due to pudendal neuralgia: a systematic review
Abstract
Background: The pudendal nerve is considered as the main nerve of sexuality. Pudendal neuralgia is an underdiagnosed disease in clinical practice. The aim of this systematic review is to highlight the role of pudendal neuralgia on sexual dysfunction in both sexes.
Methods: A PubMed search was performed using the following keywords: "Pudendal" AND "Sexual dysfunction" or "Erectile dysfunction" or "Ejaculation" or "Persistent sexual arousal" or "Dyspareunia" or "Vulvodynia". The search involved patients having sexual dysfunction due to pudendal neuralgia. Treatment received was also reported.
Results: Five case series, seven cohort studies, two pilot studies, and three randomized clinical trials were included in this systematic review. Pudendal nerve and/or artery entrapment, or pudendal neuralgia, is a reversible cause of multiple sexual dysfunctions. Interventions such as anesthetic injections, neurolysis, and decompression are reported as potential treatment modalities. There are no studies describing the role of pudendal canal syndrome in the pathophysiology or treatment of delayed ejaculation or penile shortening.
Discussion: Pudendal neuralgia is an underestimated yet important cause of persistent genital arousal, erectile dysfunction (ED), premature ejaculation (PE), ejaculation pain, and vulvodynia. Physicians should be aware of this entity and examine the pudendal canal in such patients before concluding an idiopathic cause of sexual dysfunction.
Keywords: Pudendal nerve; ejaculation; erectile dysfunction (ED); sexual dysfunction; sexuality.
2021 Translational Andrology and Urology. All rights reserved.
Conflict of interest statement
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/tau-21-13). The authors have no conflicts of interest to declare.
Comment in
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Pudendal nerve lesions in young men with erectile dysfunction: imaging with 3T magnetic resonance neurography.Asian J Androl. 2023 Sep 1;25(5):650-652. doi: 10.4103/aja202293. Epub 2023 Jan 10. Asian J Androl. 2023. PMID: 36629161 Free PMC article. No abstract available.
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