Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jul;26(29):2100186.
doi: 10.2807/1560-7917.ES.2021.26.29.2100186.

Transmission of paediatric respiratory syncytial virus and influenza in the wake of the COVID-19 pandemic

Affiliations

Transmission of paediatric respiratory syncytial virus and influenza in the wake of the COVID-19 pandemic

Thomas C Williams et al. Euro Surveill. 2021 Jul.

Abstract

The non-pharmaceutical interventions implemented to slow the spread of SARS-CoV-2 have had consequences on the transmission of other respiratory viruses, most notably paediatric respiratory syncytial virus (RSV) and influenza. At the beginning of 2020, lockdown measures in the southern hemisphere led to a winter season with a marked reduction in both infections. Intermittent lockdowns in the northern hemisphere also appeared to interrupt transmission during winter 2020/21. However, a number of southern and northern hemisphere countries have now seen delayed RSV peaks. We examine the implications of these unpredictable disease dynamics for health service delivery in Europe, such as paediatric hospital and intensive care bed space planning, or palivizumab prophylaxis. We discuss the challenges for RSV vaccine trials and influenza immunisation campaigns, and highlight the considerable research opportunities that have arisen with the SARS-CoV-2 pandemic. We argue that the rapid advances in viral whole genome sequencing, phylogenetic analysis, and open data sharing during the pandemic are applicable to the ongoing surveillance of RSV and influenza. Lastly, we outline actions to prepare for forthcoming influenza seasons and for future implementation of RSV vaccines.

Keywords: Respiratory Syncytial Virus; influenza; respiratory infections.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: None declared.

References

    1. Shi T, McAllister DA, O’Brien KL, Simoes EAF, Madhi SA, Gessner BD, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study. Lancet. 2017;390(10098):946-58. 10.1016/S0140-6736(17)30938-8 - DOI - PMC - PubMed
    1. Wang X, Li Y, O’Brien KL, Madhi SA, Widdowson MA, Byass P, et al. Global burden of respiratory infections associated with seasonal influenza in children under 5 years in 2018: a systematic review and modelling study. Lancet Glob Health. 2020;8(4):e497-510. 10.1016/S2214-109X(19)30545-5 - DOI - PMC - PubMed
    1. Britton PN, Hu N, Saravanos G, Shrapnel J, Davis J, Snelling T, et al. Lancet Child Adolesc Health. 2020;4(11):e42-3. 10.1016/S2352-4642(20)30307-2 - DOI - PMC - PubMed
    1. Olsen SJ, Azziz-Baumgartner E, Budd AP, Brammer L, Sullivan S, Pineda RF, et al. Decreased influenza activity during the COVID-19 pandemic - United States, Australia, Chile, and South Africa, 2020. MMWR Morb Mortal Wkly Rep. 2020;69(37):1305-9. 10.15585/mmwr.mm6937a6 - DOI - PMC - PubMed
    1. Vásquez-Hoyos P, Diaz-Rubio F, Monteverde-Fernandez N, Jaramillo-Bustamante JC, Carvajal C, Serra A, et al. Reduced PICU respiratory admissions during COVID-19. Arch Dis Child 2020:archdischild-2020-320469 - PubMed

Publication types