Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jul;26(29):2100630.
doi: 10.2807/1560-7917.ES.2021.26.29.2100630.

Characteristics of the delayed respiratory syncytial virus epidemic, 2020/2021, Rhône Loire, France

Jean-Sebastien Casalegno  1   2   3   4 , Dominique Ploin  3   5 , Aymeric Cantais  6   7 , Elsa Masson  4   5 , Emilie Bard  4   5 , Martine Valette  1   2   3 , Remi Fanget  1   2   3 , Sandrine Couray Targe  8 , Anne-Florence Myar-Dury  8 , Muriel Doret-Dion  4   9 , Mona Massoud  9 , Gregory Queromes  3   4 , Philippe Vanhems  10   11   4 , Olivier Claris  12   4 , Marine Butin  13   4 , Sylvie Pillet  14   7 , Florence Ader  15   4 , Sylvie Bin  13 , Alexandre Gaymard  1   2   3   4 , Bruno Lina  1   2   3   4 , Florence Morfin  1   2   3   4 ; VRS study group in Lyon  16 ; Etienne Javouhey  4   5 , Yves Gillet  4   5
Collaborators, Affiliations

Characteristics of the delayed respiratory syncytial virus epidemic, 2020/2021, Rhône Loire, France

Jean-Sebastien Casalegno et al. Euro Surveill. 2021 Jul.

Abstract

The Rhône-Loire metropolitan areas' 2020/21 respiratory syncytial virus (RSV) epidemic was delayed following the implementation of non-pharmaceutical interventions (NPI), compared with previous seasons. Very severe lower respiratory tract infection incidence among infants ≤ 3 months decreased twofold, the proportion of cases among children aged > 3 months to 5 years increased, and cases among adults > 65 years were markedly reduced. NPI appeared to reduce the RSV burden among at-risk groups, and should be promoted to minimise impact of future RSV outbreaks.

Trial registration: ClinicalTrials.gov NCT04944160.

Keywords: COVID-19; RSV; SARI; SARS-CoV-2; bronchiolitis; disease burden; non-pharmacological interventions; pharmacological interventions.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Number of laboratory-confirmed respiratory syncytial virus cases by week, university hospitals of Lyon and Saint-Etienne, France, epidemiological seasons 2018/19−2020/21
Figure 2
Figure 2
Age pyramid of respiratory syncytial virus cases by epidemiological season, university hospitals of Lyon and Saint-Etienne, France, epidemiological seasons 2018/19−2020/21a
See this image and copyright information in PMC

References

    1. Cowling BJ, Ali ST, Ng TWY, Tsang TK, Li JCM, Fong MW, et al. Impact assessment of non-pharmaceutical interventions against coronavirus disease 2019 and influenza in Hong Kong: an observational study. Lancet Public Health. 2020;5(5):e279-88. 10.1016/S2468-2667(20)30090-6 - DOI - PMC - PubMed
    1. Foley DA, Yeoh DK, Minney-Smith CA, Martin AC, Mace AO, Sikazwe CT, et al. The Interseasonal Resurgence of Respiratory Syncytial Virus in Australian Children Following the Reduction of Coronavirus Disease 2019-Related Public Health Measures. Clin Infect Dis. 2021;ciaa1906. http://dx.doi.org / 10.1093/cid/ciaa1906 PMID:33594407 - DOI - PMC - PubMed
    1. National Institute for Communicable Diseases (NICD). Weekly Respiratory Pathogens Surveillance Report 2021. Johannesburg: NICD; 2021. Available from: https://www.nicd.ac.za/diseases-a-z-index/covid-19/surveillance-reports/...
    1. Casalegno JS, Javouhey E, Ploin D, Valette M, Fanget R, Couray-Targe S, et al. Delayed Start of the Respiratory Syncytial Virus Epidemic at the End of the 20/21 Northern Hemisphere Winter Season, Lyon, France. MedRxiv 2021.03.12.21253446. 2021. Available from: https://www.medrxiv.org/content/10.1101/2021.03.12.21253446v1 - DOI
    1. Delestrain C, Danis K, Hau I, Billard MN, Kragten L, Cohen R, et al. Impact of COVID-19 social distancing on viral infection in France: a delayed outbreak of RSV. Authorea. 2021 Available from: https://www.authorea.com/users/333160/articles/517042-impact-of-covid-19... - PMC - PubMed

Associated data