Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Oct;42(10):3969-3971.
doi: 10.1007/s10072-021-05442-5. Epub 2021 Jul 23.

Stress related to COVID-19 pandemic as a trigger for disease activity in multiple sclerosis: a case report

Antonino Giordano  1   2 , Ilaria Cetta  1   2   3 , Mario Orrico  1   2 , Federico Montini  1   2 , Francesca Sangalli  1 , Bruno Colombo  1 , Massimo Filippi  1   2   3   4 , Vittorio Martinelli  5
Affiliations
Case Reports

Stress related to COVID-19 pandemic as a trigger for disease activity in multiple sclerosis: a case report

Antonino Giordano et al. Neurol Sci. 2021 Oct.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Brain magnetic resonance imaging evolutions. A MRI in January 2020 showing focal hyperintense lesions on axial FLAIR sequence (left) with no contrast enhancement on T1-weighted sequence after gadolinium administration (right). B MRI control in June 2020 showing several new hyperintense lesions on sagittal FLAIR sequences (left) with post-contrast enhancement at T1-weighted sequences (right). C FLAIR (left) and post-contrast T1 (right) sagittal sequences at MRI examination in July 2020 showing significant improvement after intravenous steroid treatment
See this image and copyright information in PMC

References

    1. Galeotti C, Bayry J. Autoimmune and inflammatory diseases following COVID-19. Nat Rev Rheumatol. 2020;16(8):413–414. doi: 10.1038/s41584-020-0448-7. - DOI - PMC - PubMed
    1. Toscano G, Palmerini F, Ravaglia S, et al. Guillain-Barré syndrome associated with SARS-CoV-2. N Engl J Med. 2020;382(26):2574–2576. doi: 10.1056/NEJMc2009191. - DOI - PMC - PubMed
    1. Artemiadis AK, Anagnostouli MC, Alexopoulos EC. Stress as a risk factor for multiple sclerosis onset or relapse: a systematic review. Neuroepidemiology. 2011;36:109–120. doi: 10.1159/000323953. - DOI - PubMed
    1. Mohr DC, Pelletier D. A temporal framework for understanding the effects of stressful life events on inflammation in patients with multiple sclerosis. Brain Behav Immun. 2006;20(1):27–36. doi: 10.1016/j.bbi.2005.03.011. - DOI - PubMed
    1. Giordano A, Schwarz G, Cacciaguerra L, et al. COVID-19: can we learn from encephalitis lethargica? Lancet Neurol. 2020;19(7):570. doi: 10.1016/S1474-4422(20)30189-7. - DOI - PMC - PubMed