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. 2021 Nov;41(11):3861-3867.
doi: 10.1007/s10792-021-01957-0. Epub 2021 Jul 23.

Primary congenital glaucoma surgery: outcomes and visual function

Elena Gusson  1 , Francesca Chemello  1 , Rosa Longo  2 , Elia Franzolin  1 , Roberta Vesentini  3 , Giuseppe Verlato  3 , Giorgio Marchini  1
Affiliations

Primary congenital glaucoma surgery: outcomes and visual function

Elena Gusson et al. Int Ophthalmol. 2021 Nov.

Abstract

Purpose: To assess the long-term visual outcomes of children with PCG, irrespective of the type of surgical procedure, and to create visual acuity curves to help in predicting the development of visual function in these patients. The secondary aim is to identify associated factors for visual decline or loss, highlighting differences between neonatal and infantile subgroups.

Methods: The medical records of pediatric glaucoma patients from 1996 to 2017 at the University Hospital of Verona (Verona, Italy) were retrospectively reviewed. Visual acuities, surgeries, PCG subtype and etiology of vision impairment were recorded. Statistical analyses were performed to detect factors associated with vision decline.

Results: Sixty-seven eyes (40 patients) were included in the study. Developmental predictive curves of visual acuity showed that children with infantile PCG had a better visual outcome than children with neonatal PCG at each step of follow-up. A good-to-moderate VA (< 1 LogMAR) was achieved in 56 eyes (83.6%), while 11 eyes (16.4%) had poor VA (≥ 1 LogMAR). The age at onset, sex, number of surgeries, intraocular pressure (IOP) control (with or without antiglaucoma drugs), axial length (AL) and corneal opacities were statistically associated with vision impairment (p < 0.01). The main cause of visual impairment was amblyopia.

Conclusions: Visual outcomes of PCG significantly correlate with the age at diagnosis. Although a good long-term IOP control can often be achieved in PCG, often the visual acuity remains below the lower limits of the normal range. Poor vision in childhood is related to global developmental problems, and referral to third-level services should not be delayed to prevent vision impairment. In this regard, visual acuity curves can be a useful tool for the consultant ophthalmologist to define the visual development of children affected by PCG.

Keywords: Axial length; Childhood glaucoma; Glaucoma surgery; Intraocular pressure; Visual acuity.

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Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
Axial length (AL) with increasing age during follow-up in childhood glaucoma as compared to age-matched normal value
Fig. 2
Fig. 2
BCVA with increasing age during follow-up in childhood glaucoma as compared to age-matched normal value
See this image and copyright information in PMC

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