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Review
. 2021 Sep;10(3):290-300.
doi: 10.1007/s13679-021-00450-0. Epub 2021 Jul 23.

Endoscopic Procedures for Weight Loss

Vitor Ottoboni Brunaldi  1   2 , Manoel Galvao Neto  3   4
Affiliations
Review

Endoscopic Procedures for Weight Loss

Vitor Ottoboni Brunaldi et al. Curr Obes Rep. 2021 Sep.

Abstract

Purpose of review: To provide updated evidence on the endoscopic procedures for weight loss and to bring personal insights on the future of endobariatrics.

Recent findings: Intragastric balloons promote significant improvement in histologic and radiologic aspects of non-alcoholic steatohepatitis; the endoscopic sleeve gastroplasty is effective up to 5 years and seems particularly beneficial to patients with BMI≤40kg/m2; distal POSE is a promising technique but still lacks adequate clinical data; aspiration therapy triggers remarkable weight loss, but data on weight trends after removal of the device are still lacking; the satiety-inducing device, the sleeveballoon, the gastric mucosal devitalization, and the endoscopic magnetic partial jejunal diversion are promising procedures still under study and refinements. Several therapeutic options are necessary during obesity's natural history. Therefore, endobariatrics should act in harmony with lifestyle interventions, diet modification, psychological treatment, pharmacotherapy, and bariatric surgery seeking the best outcome in the long term.

Keywords: Bariatric; Duodenal liner; Duodenal mucosal resurfacing; Endoscopy; Intragastric balloon; Jejunal diversion; Obesity; Overweight; Type 2 diabetes; Weight loss.

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Figures

Figure 1
Figure 1
A proposed step-up therapeutic approach for obesity combining all available therapies. ESG, endoscopic sleeve gastroplasty; TORE, transoral outlet reduction. Courtesy of Dr. Ana Carolina Hoff.
See this image and copyright information in PMC

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