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Comment
. 2021 Jul 22;184(15):3845-3847.
doi: 10.1016/j.cell.2021.06.026.

Unraveling the long-term effect of influenza vaccines

Maria Rescigno  1
Affiliations
Comment

Unraveling the long-term effect of influenza vaccines

Maria Rescigno. Cell. .

Abstract

The past decade has witnessed the emergence of highly sophisticated vaccines; still their mechanism of action is not fully understood. Wimmers et al. use advanced techniques to evaluate the immune landscape induced by flu vaccines and show that their effect on the immune system can last even 6 months from administration.

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  • The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination.
    Wimmers F, Donato M, Kuo A, Ashuach T, Gupta S, Li C, Dvorak M, Foecke MH, Chang SE, Hagan T, De Jong SE, Maecker HT, van der Most R, Cheung P, Cortese M, Bosinger SE, Davis M, Rouphael N, Subramaniam S, Yosef N, Utz PJ, Khatri P, Pulendran B. Wimmers F, et al. Cell. 2021 Jul 22;184(15):3915-3935.e21. doi: 10.1016/j.cell.2021.05.039. Epub 2021 Jun 25. Cell. 2021. PMID: 34174187 Free PMC article. Clinical Trial.

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