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. 2021 Jul 13;18(14):7446.
doi: 10.3390/ijerph18147446.

Antiretroviral Therapy (ART) Adherence and Prenatal Alcohol Use among Women Who Are Pregnant with HIV in South Africa

Yukiko Washio  1   2 , Felicia A Browne  1   3 , Jacqueline Ndirangu  1 , Tracy L Kline  1 , Wendee M Wechsberg  1   3   4   5
Affiliations

Antiretroviral Therapy (ART) Adherence and Prenatal Alcohol Use among Women Who Are Pregnant with HIV in South Africa

Yukiko Washio et al. Int J Environ Res Public Health. .

Abstract

This brief report emphasizes the need to focus on women with HIV who are pregnant who use alcohol or other drugs. A recently completed implementation science study tested a gender-focused behavioral intervention, the Women's Health CoOp (WHC), to improve antiretroviral therapy (ART) adherence and reduce alcohol use among women with HIV. The study identified 33 participants who had a positive pregnancy test result at the baseline assessment, of whom five participants remained pregnant during the 6-month duration of the study. Of the 33 pregnant participants at the baseline assessment, 55% reported past-month alcohol use, with 27% reporting a history of physical abuse and 12% reporting a history of sexual abuse. The five women who remained pregnant at 6 months showed improved ART adherence and reduced prenatal alcohol use. The gender-focused WHC intervention shows promise as a cost-effective, sustainable, behavioral intervention to address these intersecting syndemic issues. Future research should focus on identifying the needs of women with HIV who are pregnant who use alcohol or other drugs and developing tailored evidence-based behavioral interventions such as the WHC for preventing FASD in addition to improving ART adherence in this key population of women and reducing the economic burden on society.

Keywords: ART adherence; South Africa; brief behavioral intervention; fetal alcohol spectrum disorders; prenatal alcohol use.

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Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Avert HIV and AIDS in South Africa. [(accessed on 9 July 2021)];2019 Available online: https://www.avert.org/professionals/hiv-around-world/sub-saharan-africa/....
    1. Gielen A.C., Ghandour R.M., Burke J.G., Mahoney P., McDonnell K.A., O’Campo P. HIV/AIDS and intimate partner violence: Intersecting women’s health issues in the United States. Trauma Violence Abus. 2007;8:178–198. doi: 10.1177/1524838007301476. - DOI - PubMed
    1. Russell B.S., Eaton L.A., Petersen-Williams P. Intersecting epidemics among pregnant women: Alcohol use, interpersonal violence, and HIV infection in South Africa. Curr. HIV/AIDS Rep. 2012;10:103–110. doi: 10.1007/s11904-012-0145-5. - DOI - PMC - PubMed
    1. Lange S., Probst C., Gmel G., Rehm J., Burd L., Popova S. Global prevalence of fetal alcohol spectrum disorder among Children and Youth: A Systematic Review and Meta-analysis. Obstet. Gynecol. Surv. 2018;73:189–191. doi: 10.1097/01.ogx.0000532194.88210.00. - DOI - PMC - PubMed
    1. Abel E.L., Sokol R.J. Incidence of fetal alcohol syndrome and economic impact of FAS-related anomalies. Drug Alcohol. Depend. 1987;19:51–70. doi: 10.1016/0376-8716(87)90087-1. - DOI - PubMed

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