One step closer to pharmacotherapy for sleep apnoea
- PMID: 34302301
- DOI: 10.1113/JP282061
One step closer to pharmacotherapy for sleep apnoea
Keywords: genioglossus; hyoscine buytlbromide; randomised-controlled trial; reboxetine; sleep-disordered breathing.
Comment on
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The noradrenergic agent reboxetine plus the antimuscarinic hyoscine butylbromide reduces sleep apnoea severity: a double-blind, placebo-controlled, randomised crossover trial.J Physiol. 2021 Sep;599(17):4183-4195. doi: 10.1113/JP281912. Epub 2021 Jul 14. J Physiol. 2021. PMID: 34174090 Clinical Trial.
References
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- Lim R, Carberry JC, Wellman A, Grunstein R & Eckert DJ (2019). Reboxetine and hyoscine butylbromide improve upper airway function during nonrapid eye movement and suppress rapid eye movement sleep in healthy individuals. Sleep 42, zsy261.
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- Lim R, Messineo L, Grunstein RR, Carberry JC & Eckert DJ (2021). The noradrenergic agent reboxetine plus antimuscarinic hyoscine butylbromide reduces sleep apnoea severity: A double-blind, placebo-controlled, randomised crossover trial. J Physiol 599, 4183-4195.
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