Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Sep;112(3):1005-1022.
doi: 10.1016/j.athoracsur.2021.05.001. Epub 2021 Jul 22.

Summary: International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes

Hector I Michelena  1 , Alessandro Della Corte  2 , Arturo Evangelista  3 , Joseph J Maleszewski  4 , William D Edwards  4 , Mary J Roman  5 , Richard B Devereux  5 , Borja Fernández  6 , Federico M Asch  7 , Alex J Barker  8 , Lilia M Sierra-Galan  9 , Laurent De Kerchove  10 , Susan M Fernandes  11 , Paul W M Fedak  12 , Evaldas Girdauskas  13 , Victoria Delgado  14 , Suhny Abbara  15 , Emmanuel Lansac  16 , Siddharth K Prakash  17 , Malenka M Bissell  18 , Bogdan A Popescu  19 , Michael D Hope  20 , Marta Sitges  21 , Vinod H Thourani  22 , Phillippe Pibarot  23 , Krishnaswamy Chandrasekaran  24 , Patrizio Lancellotti  25 , Michael A Borger  26 , John K Forrest  27 , John Webb  28 , Dianna M Milewicz  17 , Raj Makkar  29 , Martin B Leon  30 , Stephen P Sanders  31 , Michael Markl  32 , Victor A Ferrari  33 , William C Roberts  34 , Jae-Kwan Song  35 , Philipp Blanke  36 , Charles S White  37 , Samuel Siu  38 , Lars G Svensson  39 , Alan C Braverman  40 , Joseph Bavaria  41 , Thoralf M Sundt  42 , Gebrine El Khoury  10 , Ruggero De Paulis  43 , Maurice Enriquez-Sarano  24 , Jeroen J Bax  14 , Catherine M Otto  44 , Hans-Joachim Schäfers  45
Affiliations
Free article

Summary: International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes

Hector I Michelena et al. Ann Thorac Surg. 2021 Sep.
Free article

Abstract

This International evidence-based nomenclature and classification consensus on the congenital bicuspid aortic valve and its aortopathy recognizes 3 types of bicuspid aortic valve: 1. Fused type, with 3 phenotypes: right-left cusp fusion, right-non cusp fusion and left-non cusp fusion; 2. 2-sinus type with 2 phenotypes: Latero-lateral and antero-posterior; and 3. Partial-fusion or forme fruste. This consensus recognizes 3 bicuspid-aortopathy types: 1. Ascending phenotype; root phenotype; and 3. extended phenotypes.

PubMed Disclaimer

Similar articles

  • International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes.
    Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, El Khoury G, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ. Michelena HI, et al. Ann Thorac Surg. 2021 Sep;112(3):e203-e235. doi: 10.1016/j.athoracsur.2020.08.119. Epub 2021 Jul 22. Ann Thorac Surg. 2021. PMID: 34304860
  • Summary: International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional, and research purposes.
    Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, Khoury GE, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ. Michelena HI, et al. J Thorac Cardiovasc Surg. 2021 Sep;162(3):781-797. doi: 10.1016/j.jtcvs.2021.05.008. Epub 2021 Jul 22. J Thorac Cardiovasc Surg. 2021. PMID: 34304894 Review.
  • International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes.
    Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, El Khoury G, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ. Michelena HI, et al. J Thorac Cardiovasc Surg. 2021 Sep;162(3):e383-e414. doi: 10.1016/j.jtcvs.2021.06.019. Epub 2021 Jul 22. J Thorac Cardiovasc Surg. 2021. PMID: 34304896 Review.
  • Summary: international consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes.
    Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, Khoury GE, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ. Michelena HI, et al. Eur J Cardiothorac Surg. 2021 Sep 11;60(3):481-496. doi: 10.1093/ejcts/ezab039. Eur J Cardiothorac Surg. 2021. PMID: 34292332
  • International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes.
    Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, El Khoury G, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ; Endorsed by the Heart Valve Society (HVS), European Association of Cardiovascular Imaging (EACVI), Society of Thoracic Surgeons (STS), American Association for Thoracic Surgery (AATS), Society for Cardiovascular Magnetic Resonance (SCMR), Society of Cardiovascular Computed Tomography (SCCT), North American Society for Cardiovascular Imaging (NASCI) and the International Bicuspid Aortic Valve Consortium (BAVCon). Michelena HI, et al. Eur J Cardiothorac Surg. 2021 Sep 11;60(3):448-476. doi: 10.1093/ejcts/ezab038. Eur J Cardiothorac Surg. 2021. PMID: 34293102
See all similar articles

Cited by

  • Unraveling Bicuspid Aortic Valve Enigmas by Multimodality Imaging: Clinical Implications.
    Evangelista Masip A, Galian-Gay L, Guala A, Lopez-Sainz A, Teixido-Turà G, Ruiz Muñoz A, Valente F, Gutierrez L, Fernandez-Galera R, Casas G, Panaro A, Marigliano A, Huguet M, González-Alujas T, Rodriguez-Palomares J. Evangelista Masip A, et al. J Clin Med. 2022 Jan 17;11(2):456. doi: 10.3390/jcm11020456. J Clin Med. 2022. PMID: 35054153 Free PMC article. Review.
  • Navigating the challenges of bicuspid aortic valve-aortopathy.
    Kanagala SG, Sawhney A, Parikh K, Gupta V, Mahmood T, Anamika F, Jain R, Garg N. Kanagala SG, et al. Glob Cardiol Sci Pract. 2023 Sep 30;2023(4):e202327. doi: 10.21542/gcsp.2023.27. eCollection 2023 Sep 30. Glob Cardiol Sci Pract. 2023. PMID: 38404628 Free PMC article. Review.

Publication types

MeSH terms

LinkOut - more resources