Summary: International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes

Hector I Michelena¹, Alessandro Della Corte², Arturo Evangelista³, Joseph J Maleszewski⁴, William D Edwards⁴, Mary J Roman⁵, Richard B Devereux⁵, Borja Fernández⁶, Federico M Asch⁷, Alex J Barker⁸, Lilia M Sierra-Galan⁹, Laurent De Kerchove¹⁰, Susan M Fernandes¹¹, Paul W M Fedak¹², Evaldas Girdauskas¹³, Victoria Delgado¹⁴, Suhny Abbara¹⁵, Emmanuel Lansac¹⁶, Siddharth K Prakash¹⁷, Malenka M Bissell¹⁸, Bogdan A Popescu¹⁹, Michael D Hope²⁰, Marta Sitges²¹, Vinod H Thourani²², Phillippe Pibarot²³, Krishnaswamy Chandrasekaran²⁴, Patrizio Lancellotti²⁵, Michael A Borger²⁶, John K Forrest²⁷, John Webb²⁸, Dianna M Milewicz¹⁷, Raj Makkar²⁹, Martin B Leon³⁰, Stephen P Sanders³¹, Michael Markl³², Victor A Ferrari³³, William C Roberts³⁴, Jae-Kwan Song³⁵, Philipp Blanke³⁶, Charles S White³⁷, Samuel Siu³⁸, Lars G Svensson³⁹, Alan C Braverman⁴⁰, Joseph Bavaria⁴¹, Thoralf M Sundt⁴², Gebrine El Khoury¹⁰, Ruggero De Paulis⁴³, Maurice Enriquez-Sarano²⁴, Jeroen J Bax¹⁴, Catherine M Otto⁴⁴, Hans-Joachim Schäfers⁴⁵

Affiliations

¹ Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota. Electronic address: michelena.hector@mayo.edu.
² Department of Translational Medical Sciences, University of Campania "L. Vanvitelli", Naples, Italy.
³ Department of Cardiology, Hospital Vall d'Hebron, Vall d'Hebron Research Institute (VHIR) Ciber-CV, Barcelona, Spain.
⁴ Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
⁵ Division of Cardiology, Weill Cornell Medicine, New York, New York.
⁶ Departamento de Biología Animal, Facultad de Ciencias, Instituto de Investigación Biomédica de Málaga, Universidad de Málaga, Ciber-CV, Málaga, Spain.
⁷ MedStar Health Research Institute, Washington, DC.
⁸ Department of Radiology, Children's Hospital Colorado, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
⁹ Cardiovascular Division, American British Cowdray Medical Center, Mexico City, Mexico.
¹⁰ Division of Cardiothoracic and Vascular Surgery, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.
¹¹ Division of Pediatric Cardiology, Department of Pediatrics, Stanford University, Palo Alto, California; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Palo Alto, California.
¹² Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
¹³ Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Hamburg, Germany.
¹⁴ Department of Cardiology, Leiden University Medical Center, Leiden, Netherlands.
¹⁵ Cardiothoracic Imaging Division, Department of Radiology, UT Southwestern Medical Center, Dallas, Texas.
¹⁶ Department of Cardiac Surgery, Institute Mutualiste Montsouris, Paris, France.
¹⁷ Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.
¹⁸ Department of Biomedical Imaging Science, Leeds Institute to Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom.
¹⁹ Department of Cardiology, University of Medicine and Pharmacy "Carol Davila"-Euroecolab, Emergency Institute for Cardiovascular Diseases "Prof. Dr. C. C. Iliescu", Bucharest, Romania.
²⁰ Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California.
²¹ Cardiovascular Institute, Hospital Clínic, Universitat de Barcelona, IDIBAPS, CIBERCV, ISCIII (CB16/11/00354), CERCA Programme, Barcelona, Spain.
²² Department of Cardiovascular Surgery, Marcus Valve Center, Piedmont Heart Institute, Atlanta, Georgia.
²³ Department of Cardiology, Québec Heart & Lung Institute, Laval University Québec, Québec, Canada.
²⁴ Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
²⁵ Department of Cardiology, University of Liège Hospital, GIGA Cardiovascular Sciences, CHU Sart Tilman, Liège, Belgium; Gruppo Villa Maria Care and Research, Maria Cecilia Hospital, Cotignola, and Anthea Hospital, Bari, Italy.
²⁶ University Clinic of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
²⁷ Yale University School of Medicine & Yale New Haven Hospital, New Haven, Connecticut.
²⁸ St Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
²⁹ Cedars Sinai Heart Institute, Los Angeles, California.
³⁰ Division of Cardiology, Columbia University Irving Medical Center/NY Presbyterian Hospital, New York, New York.
³¹ Cardiac Registry, Departments of Cardiology, Pathology and Cardiac Surgery, Boston Children's Hospital, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.
³² Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
³³ Cardiovascular Medicine Division, University of Pennsylvania Medical Center and Penn Cardiovascular Institute, Philadelphia, Pennsylvania.
³⁴ Baylor Heart and Vascular Institute, Baylor University Medical Center, Texas A & M School of Medicine, Dallas Campus, Dallas, Texas.
³⁵ University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
³⁶ Department of Radiology, St. Paul's Hospital, Vancouver, British Columbia, Canada.
³⁷ Department of Radiology, University of Maryland School of Medicine, Baltimore, Maryland.
³⁸ Schulich School of Medicine and Dentistry, London, Ontario, Canada.
³⁹ Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio.
⁴⁰ Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
⁴¹ Division of Cardiac Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.
⁴² Division of Cardiac Surgery, Massachusetts General Hospital, Boston, Massachusetts.
⁴³ Department of Cardiac Surgery, European Hospital and Unicamillus University Rome, Rome, Italy.
⁴⁴ Division of Cardiology, University of Washington, Seattle, Washington.
⁴⁵ Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg/ Saar, Germany.

PMID: 34304861
DOI: 10.1016/j.athoracsur.2021.05.001

Free article

Summary: International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes

Hector I Michelena et al. Ann Thorac Surg. 2021 Sep.

Free article

. 2021 Sep;112(3):1005-1022.

doi: 10.1016/j.athoracsur.2021.05.001. Epub 2021 Jul 22.

Authors

Affiliations

¹ Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota. Electronic address: michelena.hector@mayo.edu.
² Department of Translational Medical Sciences, University of Campania "L. Vanvitelli", Naples, Italy.
³ Department of Cardiology, Hospital Vall d'Hebron, Vall d'Hebron Research Institute (VHIR) Ciber-CV, Barcelona, Spain.
⁴ Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
⁵ Division of Cardiology, Weill Cornell Medicine, New York, New York.
⁶ Departamento de Biología Animal, Facultad de Ciencias, Instituto de Investigación Biomédica de Málaga, Universidad de Málaga, Ciber-CV, Málaga, Spain.
⁷ MedStar Health Research Institute, Washington, DC.
⁸ Department of Radiology, Children's Hospital Colorado, University of Colorado, Anschutz Medical Campus, Aurora, Colorado.
⁹ Cardiovascular Division, American British Cowdray Medical Center, Mexico City, Mexico.
¹⁰ Division of Cardiothoracic and Vascular Surgery, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.
¹¹ Division of Pediatric Cardiology, Department of Pediatrics, Stanford University, Palo Alto, California; Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Palo Alto, California.
¹² Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
¹³ Department of Cardiovascular Surgery, University Heart and Vascular Center Hamburg, Hamburg, Germany.
¹⁴ Department of Cardiology, Leiden University Medical Center, Leiden, Netherlands.
¹⁵ Cardiothoracic Imaging Division, Department of Radiology, UT Southwestern Medical Center, Dallas, Texas.
¹⁶ Department of Cardiac Surgery, Institute Mutualiste Montsouris, Paris, France.
¹⁷ Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.
¹⁸ Department of Biomedical Imaging Science, Leeds Institute to Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, United Kingdom.
¹⁹ Department of Cardiology, University of Medicine and Pharmacy "Carol Davila"-Euroecolab, Emergency Institute for Cardiovascular Diseases "Prof. Dr. C. C. Iliescu", Bucharest, Romania.
²⁰ Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California.
²¹ Cardiovascular Institute, Hospital Clínic, Universitat de Barcelona, IDIBAPS, CIBERCV, ISCIII (CB16/11/00354), CERCA Programme, Barcelona, Spain.
²² Department of Cardiovascular Surgery, Marcus Valve Center, Piedmont Heart Institute, Atlanta, Georgia.
²³ Department of Cardiology, Québec Heart & Lung Institute, Laval University Québec, Québec, Canada.
²⁴ Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota.
²⁵ Department of Cardiology, University of Liège Hospital, GIGA Cardiovascular Sciences, CHU Sart Tilman, Liège, Belgium; Gruppo Villa Maria Care and Research, Maria Cecilia Hospital, Cotignola, and Anthea Hospital, Bari, Italy.
²⁶ University Clinic of Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany.
²⁷ Yale University School of Medicine & Yale New Haven Hospital, New Haven, Connecticut.
²⁸ St Paul's Hospital, University of British Columbia, Vancouver, British Columbia, Canada.
²⁹ Cedars Sinai Heart Institute, Los Angeles, California.
³⁰ Division of Cardiology, Columbia University Irving Medical Center/NY Presbyterian Hospital, New York, New York.
³¹ Cardiac Registry, Departments of Cardiology, Pathology and Cardiac Surgery, Boston Children's Hospital, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts.
³² Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
³³ Cardiovascular Medicine Division, University of Pennsylvania Medical Center and Penn Cardiovascular Institute, Philadelphia, Pennsylvania.
³⁴ Baylor Heart and Vascular Institute, Baylor University Medical Center, Texas A & M School of Medicine, Dallas Campus, Dallas, Texas.
³⁵ University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
³⁶ Department of Radiology, St. Paul's Hospital, Vancouver, British Columbia, Canada.
³⁷ Department of Radiology, University of Maryland School of Medicine, Baltimore, Maryland.
³⁸ Schulich School of Medicine and Dentistry, London, Ontario, Canada.
³⁹ Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio.
⁴⁰ Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.
⁴¹ Division of Cardiac Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.
⁴² Division of Cardiac Surgery, Massachusetts General Hospital, Boston, Massachusetts.
⁴³ Department of Cardiac Surgery, European Hospital and Unicamillus University Rome, Rome, Italy.
⁴⁴ Division of Cardiology, University of Washington, Seattle, Washington.
⁴⁵ Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg/ Saar, Germany.

PMID: 34304861
DOI: 10.1016/j.athoracsur.2021.05.001

Abstract

This International evidence-based nomenclature and classification consensus on the congenital bicuspid aortic valve and its aortopathy recognizes 3 types of bicuspid aortic valve: 1. Fused type, with 3 phenotypes: right-left cusp fusion, right-non cusp fusion and left-non cusp fusion; 2. 2-sinus type with 2 phenotypes: Latero-lateral and antero-posterior; and 3. Partial-fusion or forme fruste. This consensus recognizes 3 bicuspid-aortopathy types: 1. Ascending phenotype; root phenotype; and 3. extended phenotypes.

Copyright © 2021 The Society of Thoracic Surgeons, the American Association for Thoracic Surgery, the European Association for Cardio-Thoracic Surgery, and the Radiological Society of North America. Published by Elsevier Inc. Published by Elsevier Inc. All rights reserved.

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Summary: International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes

Affiliations

Summary: International Consensus Statement on Nomenclature and Classification of the Congenital Bicuspid Aortic Valve and Its Aortopathy, for Clinical, Surgical, Interventional and Research Purposes

Authors

Affiliations

Abstract

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LinkOut - more resources

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