Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Feb:133:108552.
doi: 10.1016/j.jsat.2021.108552. Epub 2021 Jun 24.

Changes in methadone take-home dosing before and after COVID-19

Affiliations

Changes in methadone take-home dosing before and after COVID-19

Ofer Amram et al. J Subst Abuse Treat. 2022 Feb.

Abstract

Introduction: In response to the COVID-19 pandemic, a federal exemption allowed stable and less stable patients greater take-home doses of methadone. We assessed the adoption of increased take-home medication during COVID-19 and whether increased take-home doses is associated with clients' characteristics.

Methodology: We completed a pre-post study of adults receiving methadone for OUD from an OTP in Spokane, Washington. Our outcome was the change in the number of take-home methadone doses three months before and three months after the March 2020 take-home medication exemption. Clients' characteristics included age, gender, ethnicity, education level, homelessness, spatial access to the clinic, and methamphetamine use.

Results: The study included 194 clients in treatment for a median of three years. All study participants experienced an average increase in take-home medication of 41.4 in the three-month period after the COVID-19 exemption. In the final adjusted models, clients who reported using methamphetamine in the last 30 days experienced a significantly larger increase in take-home dosage (55.6 days) compare to clients who did not use methamphetamine (p ≤0.001). Most of the clients who reported using methamphetamine were also likely to be homeless. All other variables were not associated with a change in take-home doses.

Conclusion: These results suggest that the Spokane OTP quickly expanded take-home medication dosing in response to the COVID-19 exemption and broadly expanded take-home dosing among established clients. Clients with concurrent methamphetamine use were allowed fewer take-home doses prior to COVID-19, but after the exemption the clinic provided them the same number of take-home doses as clients who had not used methamphetamine.

Keywords: Access to care; COVID-19; Methadone.

PubMed Disclaimer

Conflict of interest statement

No conflict to declare.

References

    1. (SAMHSA), S. A. a. M. H. S. A . 2020. OTP guidance for patients quarantined at home with the coronavirus.
    1. Amiri S., Lutz R., Socías E., McDonell M.G., Roll J.M., Amram O. Increased distance was associated with lower daily attendance to an opioid treatment program in Spokane County Washington. Journal of Substance Abuse Treatment. 2018;93:26–30. doi: 10.1016/j.jsat.2018.07.006. - DOI - PubMed
    1. Corsi K.F., Lehman W.K., Booth R.E. The effect of methadone maintenance on positive outcomes for opiate injection drug users. Journal of Substance Abuse Treatment. 2009;37(2):120–126. doi: 10.1016/j.jsat.2008.11.004. - DOI - PMC - PubMed
    1. Davoli M., Bargagli A.M., Perucci C.A., Schifano P., Belleudi V., Hickman M.…Faggiano F. Risk of fatal overdose during and after specialist drug treatment: The VEdeTTE study, a national multi-site prospective cohort study. Addiction. 2007;102(12):1954–1959. - PubMed
    1. Deck D., Wiitala W., McFarland B., Campbell K., Mulluly J., Krupski A., McCarty D. Medicaid coverage, methadone maintenance, and felony arrests: Outcomes of opiate treatment in two states. Journal of Addictive Diseases. 2009;28(2):89–102. doi: 10.1080/10550880902772373. - DOI - PMC - PubMed

Publication types