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. 2021 Jun 15;13(6):6362-6371.
eCollection 2021.

Regulatory effects of comprehensive psychological intervention on adverse emotions and immune status of cervical cancer patients during the perioperative period

Xiaoling Shi  1 , Li Ma  1 , Jing Hao  1 , Wenping Yan  1
Affiliations

Regulatory effects of comprehensive psychological intervention on adverse emotions and immune status of cervical cancer patients during the perioperative period

Xiaoling Shi et al. Am J Transl Res. .

Abstract

Objective: To compare and evaluate the regulatory effects of comprehensive psychological intervention on adverse emotions and immune status of cervical cancer patients during the perioperative period.

Methods: A total of 109 cervical cancer patients admitted to our hospital were selected and divided into the conventional group (n=54) and the comprehensive group (n=55). The conventional group received conventional nursing intervention, while the comprehensive group received comprehensive psychological and conventional nursing intervention. The adverse emotions, social support degrees, level of hope, sleep quality, immune functions and nursing satisfaction were compared between the two groups.

Results: On Day 10 after surgery, the comprehensive group had lower scores of hospital anxiety and depression scale-anxiety (HADS-A), and hospital anxiety and depression scale-depression (HADS-D), higher scores of social support rating scale (SSRS), intimate relationship, positive attitude, and attitude for actions, a higher excellent and good rate of social support degree (92.73% vs 75.93%), a lower Cortisol (Cor) level, and a higher level of interleukin-2 (IL-2) than the conventional group (P < 0.05). On Days 1, 3, 5, 7 and 10 after surgery, the scores of Pittsburgh sleep quality index (PSQI) in the comprehensive group were lower than those in the conventional group (P < 0.05). The overall degree of nursing satisfaction in comprehensive group (94.55%) was higher than that in the conventional group (79.63%) (P < 0.05).

Conclusion: Comprehensive psychological intervention can remarkably improve the negative emotions, social support degree, level of hope, sleep quality, immune functions, and satisfaction of cervical cancer patients receiving conventional nursing intervention during the perioperative period.

Keywords: Comprehensive psychological intervention; adverse emotions; cervical cancer; immune status; perioperative period; regulation.

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Conflict of interest statement

None.

Figures

Figure 1
Figure 1
Adverse emotions. On Day 3 before surgery, there was no noticeable difference in the scores of HADS-A (A) and HADS-D (B) between the two groups (P > 0.05). On Day 10 after surgery, the scores of HADS-A (A) and HADS-D (B) in the comprehensive group were lower than those in the conventional group (P < 0.05). *indicates the comparison between the two groups (P < 0.05).
Figure 2
Figure 2
Social support degree. The scores of SSRS in the comprehensive group (A) and conventional group (B) on Day 3 before surgery were lower than those in the comprehensive group (A) and conventional group (B) on Day 10 after surgery (P > 0.05). On Day 10 after surgery, the scores of SSRS in the comprehensive group (C) were higher than those in the conventional group (P < 0.05). *indicates the comparison between the two groups (P < 0.05).
Figure 3
Figure 3
Level of hope. On Day 3 before surgery, there was no significant difference in the scores of intimate relationship (A), positive attitude (B) and attitude for actions (C) between the two groups (P > 0.05). On Day 10 after surgery, the scores of intimate relationship (A), positive attitude (B) and attitude for actions (C) in the comprehensive group were higher that those in the conventional group (P < 0.05). *indicates the comparison between the two groups (P < 0.05).
Figure 4
Figure 4
Sleep quality. On Day 3 before surgery, there was no marked difference in the scores of PSQI between the two groups (P > 0.05). On Days 1, 3, 5, 7 and 10 after surgery, the scores of PSQI in the comprehensive group were lower than those in the conventional group (P < 0.05). *indicates the comparison between the two groups (P < 0.05).
Figure 5
Figure 5
Cor and IL-2. On Day 3 before surgery, there was no significant difference in the levels of Cor (A) and IL-2 (B) between the two groups (P > 0.05). On Day 10 after surgery, the comprehensive group had a lower level of Cor (A) and a higher level of IL-2 (B) compared with the conventional group (P < 0.05). *indicates the comparison between the two groups (P < 0.05).
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References

    1. Fang J, Zhang H, Jin S. Epigenetics and cervical cancer: from pathogenesis to therapy. Tumour Biol. 2014;35:5083–5093. - PubMed
    1. Olusola P, Banerjee HN, Philley JV, Dasgupta S. Human papilloma virus-associated cervical cancer and health disparities. Cells. 2019;8:622. - PMC - PubMed
    1. Bogani G, Leone Roberti Maggiore U, Rossetti D, Ditto A, Martinelli F, Chiappa V, Ferla S, Indini A, Sabatucci I, Lorusso D, Raspagliesi F. Advances in laparoscopic surgery for cervical cancer. Crit Rev Oncol Hematol. 2019;143:76–80. - PubMed
    1. McCree R, Giattas MR, Sahasrabuddhe VV, Jolly PE, Martin MY, Usdan SL, Kohler C, Lisovicz N. Expanding cervical cancer screening and treatment in tanzania: stakeholders’ perceptions of structural influences on scale-up. Oncologist. 2015;20:621–626. - PMC - PubMed
    1. Lestyani Nasution C, Afiyanti Y, Milanti A. The relationship of the preexisting anxiety problem with the demographic profile of cervical cancer patients. Enferm Clin. 2018;28(Suppl 1):199–202. - PubMed

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