Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2021 Jun 15;13(6):7047-7052.
eCollection 2021.

Early and late outcomes of non-total aortic arch replacement for repair of acute Stanford Type A aortic dissection

Zhifa Zheng  1 , Lingbo Yang  1 , Zhongjie Zhang  1 , Dong Wang  1 , Junqing Zong  1 , Likui Zhang  1 , Xuening Wang  1
Affiliations

Early and late outcomes of non-total aortic arch replacement for repair of acute Stanford Type A aortic dissection

Zhifa Zheng et al. Am J Transl Res. .

Abstract

Objective: This study evaluated the early and late outcomes of non-total aortic arch replacement for acute Stanford A aortic dissection.

Methods: 131 cases of acute Stanford Type A aortic dissection with no rupture admitted to our hospital from January 2016 to December 2019 were selected for non-total aortic arch replacement. According to different surgical methods, 51 patients with tear-oriented ascending/hemiarch replacement were included in Group A, and 80 patients who underwent total arch replacement surgery were enrolled in Group B. The perioperative indicators, 30-day mortality rate, and the incidence of postoperative complications were compared between the two groups, and the survival rate of patients were compared by follow-up after discharge.

Results: The cardiopulmonary bypass time, cardiac perfusion time, invasive ventilation and ICU hospitalization in Group A were critically shorter than those in Group B (P<0.05). The incidence of transient cerebral dysfunction in Group A was substantially lower than that in Group B (P<0.05). The difference of comparison in perioperative mortality, incidence of permanent neurological dysfunction, and incidence of acute kidney and liver damage between the two groups was statistically insignificant (P>0.05). In addition, the two groups had statistically insignificant difference in survival during postoperative follow-up (P>0.05).

Conclusion: For acute Stanford type A aortic dissection without rupture in aortic arch, the non-total aortic arch replacement has simple surgical method with high perioperative safety and long-term efficacy that similar to total arch replacement.

Keywords: Non-total aortic arch replacement; acute Stanford Type A aortic dissection; early outcome; late outcome.

PubMed Disclaimer

Conflict of interest statement

None.

Figures

Figure 1
Figure 1
Comparison of perioperative-related indexes between the two groups. Note: Compare with group A, *P<0.05.
Figure 2
Figure 2
Follow-up survival analysis of patients between the two groups.
See this image and copyright information in PMC

References

    1. Yanase Y, Ohkawa A, Inoue S, Niida Y. Stanford Type A acute aortic dissection with intimal intussusception. Ann Thorac Cardiovasc Surg. 2020;26:51–54. - PMC - PubMed
    1. Koga M, Iguchi Y, Ohara T, Tahara Y, Fukuda T, Noguchi T, Matsuda H, Minatoya K, Nagatsuka K, Toyoda K. Acute ischemic stroke as a complication of Stanford Type A acute aortic dissection: a review and proposed clinical recommendations for urgent diagnosis. Gen Thorac Cardiovasc Surg. 2018;66:439–445. - PubMed
    1. Li A, Mohetaer D, Zhao Q, Ma X, Ma Y. The relationship between renal artery involvement in Stanford B-type aortic dissection and the short-term prognosis: a single-centre retrospective cohort study. Heart Lung Circ. 2019;28:1261–1266. - PubMed
    1. Kim WH, Bae J, Choi SW, Lee JH, Kim CS, Cho HS, Lee SM. Stanford Type A aortic dissection in a patient with Marfan syndrome during pregnancy: a case report. Korean J Anesthesiol. 2016;69:76–79. - PMC - PubMed
    1. Uchida T, Kuroda Y, Yamashita A, Hamasaki A, Hirooka S, Nakai S, Kobayashi K, Sadahiro M. Clinical experience of endovascular stent-graft treatment for Stanford Type A acute aortic dissection. Kyobu Geka. 2019;72:976–983. - PubMed

LinkOut - more resources