Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2021 Jul 21;9(8):e00803.
doi: 10.1002/rcr2.803. eCollection 2021 Aug.

Idiopathic pulmonary vein thrombosis treated with apixaban

Dallis Ngo  1 , Ghulam Aftab  1 , Arjun Madhavan  1 , Amar Bukhari  1
Affiliations
Case Reports

Idiopathic pulmonary vein thrombosis treated with apixaban

Dallis Ngo et al. Respirol Case Rep. .

Abstract

Pulmonary vein thrombosis (PVT) is a rare clinical finding that is potentially fatal and with an unknown incidence rate as known cases exist predominantly in case reports. We present the case of a 58-year-old female who reported sudden onset of chest pain, shortness of breath, and dyspnoea on exertion. A computed tomography (CT) pulmonary angiogram was negative for evidence of pulmonary embolism; however, it did demonstrate the evidence of thrombosis of the right lower lobe segmental pulmonary vein. She had no identifiable aetiologies for her PVT; therefore, she was diagnosed with idiopathic PVT and was treated successfully with apixaban. This case represents the 14th incidence of idiopathic PVT in the current body of medical literature and the first case of successful treatment with apixaban.

Keywords: Apixaban; breast cancer; idiopathic; pulmonary vein thrombosis; venous thrombosis.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Axial view of a computed tomography (CT) pulmonary angiogram demonstrating a pulmonary vein thrombus (red arrow) involving the right lower lobe segmental vein.
See this image and copyright information in PMC

References

    1. Chaaya G, and Vishnubhotla P. 2017. Pulmonary vein thrombosis: a recent systematic review. Cureus 9(1):1–13. - PMC - PubMed
    1. Alexander GR, Reddi A, and Reddy D. 2009. Idiopathic pulmonary vein thrombosis: a rare cause of massive hemoptysis. Ann. Thorac. Surg. 88(1):281–283. - PubMed
    1. Selvidge SD, and Gavant ML. 1999. Idiopathic pulmonary vein thrombosis: Detection by CT and MR imaging. AJR Am. J. Roentgenol. 172(6):1639–1641. - PubMed
    1. Komatsu S, Kamata T, Imai A, et al. 2011. Idiopathic pulmonary vein thrombosis complicated with old myocardial infarction detected by multidetector row computed tomography. J. Cardiol. Cases 3(2):e94–e97. - PMC - PubMed
    1. Mumoli N, and Cei M. 2012. Idiopathic pulmonary vein thrombosis. J. Emerg. Med. 42(2):182–183. - PubMed

Publication types

LinkOut - more resources