Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021;8(3):108-115.
doi: 10.1007/s40471-021-00274-5. Epub 2021 Jul 20.

An Update on Medication Use in Older Adults: a Narrative Review

Affiliations
Review

An Update on Medication Use in Older Adults: a Narrative Review

Heather E Barry et al. Curr Epidemiol Rep. 2021.

Abstract

Purpose of review: The global phenomenon of population aging is impacting the health and care needs of society. The use of medications by older adults is acknowledged to be the most common form of medical intervention for many acute and chronic conditions and prescribing in this population continues to increase. In this narrative review, we summarise the age-related factors that should be considered when prescribing for older adults, address some of the perennial challenges related to medicine use in older people, and highlight important emerging research in this area.

Recent findings: A range of age-related factors should be considered when prescribing for older adults. However, the evidence base still lacks data pertaining to older adults due to their continued under-representation in clinical trials. Multimorbidity, polypharmacy, and inappropriate prescribing continue to remain prevalent among older adults, although recent research has been focused on the development and evaluation of complex interventions to address these challenges.

Summary: Further high-quality studies of interventions to improve and support medication use in older adults are needed, ensuring that older adults are well represented in such trials and consideration is given to the measurement of patient- and provider-focused outcomes.

Keywords: Aging; Medication adherence; Medications; Older adults; Outcome measures; Polypharmacy; Prescribing.

PubMed Disclaimer

Conflict of interest statement

Conflict of InterestThe authors declare no competing interests.

References

    1. United Nations, Department of Economic and Social Affairs, Population Divisions. World population ageing 2017 – highlights. 2017. Available at: https://www.un.org/en/development/desa/population/publications/pdf/agein.... Accessed 15 Mar 2021
    1. Sander M, Oxlund B, Jespersen A, Krasnik A, Mortensen EL, Westendorp RGJ, Rasmussen LJ. The challenges of human population ageing. Age Ageing. 2015;44(2):185–187. doi: 10.1093/ageing/afu189. - DOI - PMC - PubMed
    1. GBD 2019 Disease and Injuries Collaborators. Global burden of 369 disease and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020;396(10258):1204–1222. doi: 10.1016/S0140-6736(20)30925-9. - DOI - PMC - PubMed
    1. Dall TM, Gallo PD, Chakrabarti R, West T, Semilla AP, Storm MV. An aging population and growing disease burden will require a large and specialised health care workforce by 2025. Health Aff. 2013;32(11):2013–2020. doi: 10.1377/hlthaff.2013.0714. - DOI - PubMed
    1. World Health Organisation. Global Health Estimates. 2020. Available at: https://www.who.int/data/global-health-estimates. Accessed 26 Mar 2021

LinkOut - more resources