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Case Reports
. 2021 Jul 6;9(19):5345-5351.
doi: 10.12998/wjcc.v9.i19.5345.

Brugada syndrome associated with out-of-hospital cardiac arrest: A case report

Guo-Hua Ni  1 , Hua Jiang  2 , Li Men  3 , Yuan-Yuan Wei  4 , Dila A  3 , Xiang Ma  5
Affiliations
Case Reports

Brugada syndrome associated with out-of-hospital cardiac arrest: A case report

Guo-Hua Ni et al. World J Clin Cases. .

Abstract

Background: Brugada syndrome (BrS) is an inherited disease characterized by an electrocardiogram (ECG) with a coved-type ST-segment elevation in the right precordial leads (V1-V3), which predisposes to sudden cardiac death (SCD) due to polymorphic ventricular tachycardia or ventricular fibrillation in the absence of structural heart disease. We report the case of a 29-year-old man with out-of-hospital cardiac arrest. BrS is associated with a high incidence of SCD in adults, and increasing the awareness of BrS and prompt recognition of the Brugada ECG pattern can be lifesaving.

Case summary: A 29-year-old man suffered from out-of-hospital cardiac arrest, and after defibrillation, his ECG demonstrated a coved-type elevated ST segment in V1 and V2. These findings were compatible with type 1 Brugada pattern, and ECG of his brother showed a type 2 Brugada pattern. The diagnosis was BrS, NYHF IV, multiple organ dysfunction syndrome, sepsis, and hypoxic ischemic encephalopathy. The patient had no arrhythmia episodes after discharge throughout a follow-up period of 36 mo.

Conclusion: Increasing awareness of BrS and prompt recognition of the Brugada ECG pattern can be lifesaving.

Keywords: Brugada syndrome; Case report; Electrocardiogram; Family history; Out-of-hospital cardiac arrest; Ventricular fibrillation.

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Conflict of interest statement

Conflict-of-interest statement: The authors declare that they have no conflict of interest to report.

Figures

Figure 1
Figure 1
12-lead electrocardiogram of the patient. A and B: A typical type 1 Brugada electrocardiogram (ECG) pattern, with coved-type ST-segment elevations of > 2 mm in V1 to V2 followed by a negative T-wave in two of the right precordial leads. C: ECG recording in the ward showing the elevation of V2-V3.
Figure 2
Figure 2
12-lead electrocardiogram of the patient’s brother. A: Typical type 2 Brugada electrocardiogram (ECG) pattern, with a convex ST-segment elevation > 0.5 mm in one right precordial lead followed by a positive T-wave (after placement of leads V1 and V2 in the third and second intercostal space). B: ECG recording in the normal condition showing sinus rhythm. C: ECG recording during follow-up showing sinus rhythm.
Figure 3
Figure 3
Timeline summarizing the patient’s information, clinical findings, diagnostic tests, diagnosis, intervention, and follow-up. ECG: Electrocardiogram; SCD: Sudden cardiac death.
See this image and copyright information in PMC

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