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Case Reports
. 2021 Jun 24;8(7):ofab343.
doi: 10.1093/ofid/ofab343. eCollection 2021 Jul.

Acute Immune Thrombocytopenia (ITP) Following COVID-19 Vaccination in a Patient With Previously Stable ITP

Muzamil Jawed  1 , Amna Khalid  1 , Mayer Rubin  1 , Ramsha Shafiq  1 , Nail Cemalovic  1
Affiliations
Case Reports

Acute Immune Thrombocytopenia (ITP) Following COVID-19 Vaccination in a Patient With Previously Stable ITP

Muzamil Jawed et al. Open Forum Infect Dis. .

Abstract

Immune thrombocytopenia (ITP) is an autoimmune condition associated with multiple risk factors including viral infections (hepatitis B virus/hepatitis C virus/cytomegalovirus, HIV, and recently severe acute respiratory syndrome coronavirus 2) and vaccines. Though immune mechanisms have been proposed to explain the pathogenesis of acute ITP, autoimmunity with the coronavirus disease 2019 (COVID-19) vaccine is still unclear and needs further research. We report a case of acute ITP after administration of the Pfizer-BioNTech mRNA COVID-19 vaccine in a patient with previously stable ITP.

Keywords: COVID-19; Pfizer; SARS-CoV-2; immune thrombocytopenic purpura; vaccination.

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Figures

Figure 1.
Figure 1.
Peripheral smear with thrombocytopenia and normal red blood cell (RBC) morphology.
Figure 2.
Figure 2.
Peripheral smear with thrombocytopenia normal red blood cell (RBC) morphology.
See this image and copyright information in PMC

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