Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019;3(2):88-95.
doi: 10.24248/EAHRJ-D-19-00011. Epub 2019 Nov 29.

Retired Nurses Can Improve Retention in Prevention of Mother-to-Child Transmission Programmes

Affiliations

Retired Nurses Can Improve Retention in Prevention of Mother-to-Child Transmission Programmes

Zahra Persson Theilgaard et al. East Afr Health Res J. 2019.

Abstract

Background: The success of prevention of mother-to-child transmission (PMTCT) programmes depends on retention of mothers throughout the PMTCT cascade.

Methods: In a clinical trial of short-course combination antiretroviral therapy (cART) for PMTCT in Tanzania, senior nurses were employed to reduce the substantial loss-to-follow up (LTFU) rate.

Results: Following intervention, the relative risk (RR) of receiving a CD4 count result and antiretroviral therapy was 1.16 (95% confidence interval [CI], 1.05 to 1.27), the RR of delivery at clinic was 2.51 (95% CI, 2.06 to 3.06), the RR for reporting for follow-up at 6 to 8 weeks postpartum was 4.63 (95% CI, 3.41 to 6.27), and the RR for being retained until 9 months postpartum was 28.19 (95% CI, 11.81 to 67.28). No significant impact on transmission was found.

Conclusion: Significantly higher retention was found after senior nurses were employed. No impact on transmission was found. Relatively low transmission was found in both study arms.

PubMed Disclaimer

Conflict of interest statement

Competing Interests: None declared.

References

    1. World Health Organization (WHO). Global Guidance on Criteria and Processes for Validation: Elimination of Mother-to-Child Transmission of HIV and Syphilis. Geneva (WHO); 2014.
    1. de Vincenzi I. Triple antiretroviral compared with zidovudine and single-dose nevirapine prophylaxis during pregnancy and breastfeeding for prevention of mother-to-child transmission of HIV-1 (Kesho Bora study): a randomised controlled trial. Lancet Infect Dis. 2011;11(3):171–180. 10.1016/S1473-3099(10)70288-7. Medline - DOI - PubMed
    1. World Health Organization (WHO). Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV infection – What's New. Geneva: WHO; 2015.
    1. Theilgaard ZP, Katzenstein TL, Chiduo MG, et al. . Addressing the fear and consequences of stigmatization - a necessary step towards making HAART accessible to women in Tanzania: a qualitative study. AIDS Res Ther. 2011;8:28. 10.1186/1742-6405-8-28. Medline - DOI - PMC - PubMed
    1. Arreskov A, Minja E, Theilgaard Z, et al. . Referral success among HIV-infected women and HIV-exposed children referred for monitoring and treatment in Tanga, Tanzania. Int Health. 2010;2(1):36–41. 10.1016/j.inhe.2009.12.010. Medline - DOI - PubMed

LinkOut - more resources