Retired Nurses Can Improve Retention in Prevention of Mother-to-Child Transmission Programmes
- PMID: 34308201
- PMCID: PMC8279289
- DOI: 10.24248/EAHRJ-D-19-00011
Retired Nurses Can Improve Retention in Prevention of Mother-to-Child Transmission Programmes
Abstract
Background: The success of prevention of mother-to-child transmission (PMTCT) programmes depends on retention of mothers throughout the PMTCT cascade.
Methods: In a clinical trial of short-course combination antiretroviral therapy (cART) for PMTCT in Tanzania, senior nurses were employed to reduce the substantial loss-to-follow up (LTFU) rate.
Results: Following intervention, the relative risk (RR) of receiving a CD4 count result and antiretroviral therapy was 1.16 (95% confidence interval [CI], 1.05 to 1.27), the RR of delivery at clinic was 2.51 (95% CI, 2.06 to 3.06), the RR for reporting for follow-up at 6 to 8 weeks postpartum was 4.63 (95% CI, 3.41 to 6.27), and the RR for being retained until 9 months postpartum was 28.19 (95% CI, 11.81 to 67.28). No significant impact on transmission was found.
Conclusion: Significantly higher retention was found after senior nurses were employed. No impact on transmission was found. Relatively low transmission was found in both study arms.
© The East African Health Research Commission 2019.
Conflict of interest statement
Competing Interests: None declared.
References
-
- World Health Organization (WHO). Global Guidance on Criteria and Processes for Validation: Elimination of Mother-to-Child Transmission of HIV and Syphilis. Geneva (WHO); 2014.
-
- de Vincenzi I. Triple antiretroviral compared with zidovudine and single-dose nevirapine prophylaxis during pregnancy and breastfeeding for prevention of mother-to-child transmission of HIV-1 (Kesho Bora study): a randomised controlled trial. Lancet Infect Dis. 2011;11(3):171–180. 10.1016/S1473-3099(10)70288-7. Medline - DOI - PubMed
-
- World Health Organization (WHO). Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV infection – What's New. Geneva: WHO; 2015.
LinkOut - more resources
Full Text Sources
Research Materials