Nonalcoholic Fatty Liver Disease and Cardiac Remodeling Risk: Pathophysiological Mechanisms and Clinical Implications

Jianghua Zhou^#^{1

2

3}, Lan Bai^#^{1

3}, Xiao-Jing Zhang^{1

3}, Hongliang Li^{1

3}, Jingjing Cai^{3

4}

Affiliations

¹ Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
² Basic Medical School, Wuhan University, Wuhan, China.
³ Institute of Model Animal, Wuhan University, Wuhan, China.
⁴ Department of Cardiology, The Third Xiangya Hospital, Central South University, Changsha, China.

^# Contributed equally.

Review

Jianghua Zhou et al. Hepatology. 2021 Nov.

. 2021 Nov;74(5):2839-2847.

doi: 10.1002/hep.32072. Epub 2021 Sep 27.

Jianghua Zhou^#^{1

2

3}, Lan Bai^#^{1

3}, Xiao-Jing Zhang^{1

3}, Hongliang Li^{1

3}, Jingjing Cai^{3

4}

¹ Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
² Basic Medical School, Wuhan University, Wuhan, China.
³ Institute of Model Animal, Wuhan University, Wuhan, China.
⁴ Department of Cardiology, The Third Xiangya Hospital, Central South University, Changsha, China.

^# Contributed equally.

No abstract available

References

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1. Cai J, Zhang XJ, Ji YX, Zhang P, She ZG, Li H. Nonalcoholic fatty liver disease pandemic fuels the upsurge in cardiovascular diseases. Circ Res 2020;126:679-704.
1. Khan RS, Bril F, Cusi K, Newsome PN. Modulation of insulin resistance in nonalcoholic fatty liver disease. Hepatology 2019;70:711-724.
1. Jia G, DeMarco VG, Sowers JR. Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy. Nat Rev Endocrinol 2016;12:144-153.
1. Matthew Morris E, Fletcher JA, Thyfault JP, Rector RS. The role of angiotensin II in nonalcoholic steatohepatitis. Mol Cell Endocrinol 2013;378:29-40.