Machine Learning as a Novel Method to Support Therapeutic Drug Management and Precision Dosing

Affiliations

¹ Department of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
² Division of Clinical Pharmacology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.

Editorial

Teun van Gelder et al. Clin Pharmacol Ther. 2021 Aug.

. 2021 Aug;110(2):273-276.

doi: 10.1002/cpt.2326.

¹ Department of Clinical Pharmacy & Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
² Division of Clinical Pharmacology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.

No abstract available

Comment on

Mycophenolic Acid Exposure Prediction Using Machine Learning.
Woillard JB, Labriffe M, Debord J, Marquet P. Woillard JB, et al. Clin Pharmacol Ther. 2021 Aug;110(2):370-379. doi: 10.1002/cpt.2216. Epub 2021 Apr 6. Clin Pharmacol Ther. 2021. PMID: 33624286 Clinical Trial.

1. Thoral, P.J. et al. Sharing ICU patient data responsibly under the society of critical care medicine/European society of intensive care medicine joint data science collaboration: the Amsterdam university medical centers database (AmsterdamUMCdb) example. Crit. Care. Med. 49, e563-e577 (2021).
1. Rajkomar, A., Dean, J. & Kohane, I. Machine Learning in Medicine. N. Engl. J. Med. 380, 1347-1358 (2019).
1. Paranjape, K. et al. The value of artificial intelligence in laboratory medicine. Am. J. Clin. Pathol. 155, 823-831 (2021).
1. de Velde, F., Mouton, J.W., de Winter, B.C.M., van Gelder, T. & Koch, B.C.P. Clinical applications of population pharmacokinetic models of antibiotics: Challenges and perspectives. Pharmacol. Res. 134, 280-288 (2018).
1. Neely, M. & Jelliffe, R. Practical, individualized dosing: 21st century therapeutics and the clinical pharmacometrician. J. Clin. Pharmacol. 50, 842-847 (2010).