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. 2021 Jul 27;326(4):355-357.
doi: 10.1001/jama.2021.9380.

Effect of Systemic Hydrocortisone Initiated 7 to 14 Days After Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years' Corrected Age: Follow-up of a Randomized Clinical Trial

Nienke M Halbmeijer  1 , Wes Onland  1 , Filip Cools  2 , Renate Swarte  3 , Marja van der Heide-Jalving  4 , Maruschka P Merkus  5 , Anton H van Kaam  1 ; STOP-BPD Trial Collaborators
Collaborators, Affiliations

Effect of Systemic Hydrocortisone Initiated 7 to 14 Days After Birth in Ventilated Preterm Infants on Mortality and Neurodevelopment at 2 Years' Corrected Age: Follow-up of a Randomized Clinical Trial

Nienke M Halbmeijer et al. JAMA. .

Abstract

This follow-up to the STOP-BPD randomized clinical trial, which investigated the efficacy and safety of systemic hydrocortisone treatment initiated 7 to 14 days after birth in ventilator-dependent, very preterm infants in the Netherlands and Belgium at 36 weeks’ postmenstrual age, examines the prespecified composite of death and neurodevelopmental impairment among these infants at 2 years’ corrected age.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr van Kaam reported receiving grants from The Netherlands Organization for Health Research and Development ZonMW during the conduct of the study. No other disclosures were reported.

Comment in

References

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