Move it to lose it: Mitocytosis expels damaged mitochondria
- PMID: 34314697
- DOI: 10.1016/j.devcel.2021.07.001
Move it to lose it: Mitocytosis expels damaged mitochondria
Abstract
Mechanisms by which cells remove damaged mitochondria extracellularly are unclear. Recent work by Jiao and colleagues in Cell shows that migrating cells expel dysfunctional mitochondria in membrane-bound structures called migrasomes to maintain mitochondrial homeostasis.
Copyright © 2021 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Mitocytosis, a migrasome-mediated mitochondrial quality-control process.Cell. 2021 May 27;184(11):2896-2910.e13. doi: 10.1016/j.cell.2021.04.027. Cell. 2021. PMID: 34048705
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