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. 2021 Jul 26;31(14):R912-R914.
doi: 10.1016/j.cub.2021.06.008.

Intron splicing: U12 spliceosomal introns not so 'minor' after all

Naomi M Fast  1
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Intron splicing: U12 spliceosomal introns not so 'minor' after all

Naomi M Fast. Curr Biol. .
Free article

Abstract

Whereas most eukaryotic genes are interrupted by introns removed by the U2 (major) spliceosome, U12-type introns are extremely rare. New work uncovers a case of extensive U12-type intron gain, and an unexpectedly flexible and efficient U12 (minor) spliceosome.

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