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Case Reports
. 2020 Dec 17;3(3):357-360.
doi: 10.1016/j.jaccas.2020.12.009. eCollection 2021 Mar.

Iatrogenic Atrial Septal Defect Closure Following Mitral Transcatheter Edge-to-Edge Repair: When Do You Close?

Affiliations
Case Reports

Iatrogenic Atrial Septal Defect Closure Following Mitral Transcatheter Edge-to-Edge Repair: When Do You Close?

Mrinali Shetty et al. JACC Case Rep. .

Abstract

Transcatheter edge-to-edge repair has revolutionized the management of mitral regurgitation in the high surgical-risk population. Iatrogenic atrial septal defects (iASDs) are an obligatory consequence of the procedure. The long-term sequelae of persistent iASDs are unknown but are believed to be dependent on their size, directionality of flow, and underlying hemodynamics. We discuss an uncommon scenario of a post-transcatheter edge-to-edge repair iASD that required immediate closure. (Level of Difficulty: Intermediate.).

Keywords: GDMT, guideline-directed medical therapy; LV, left ventricular; MR, mitral regurgitation; TEE, transesophageal echocardiography; TEER, transcatheter edge-to-edge repair; cardiomyopathy; chronic heart failure; echocardiography; iASD, iatrogenic atrial septal defect; right ventricle; systolic heart failure; three-dimensional imaging; valve repair.

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Conflict of interest statement

Dr. Ricciardi has received consulting and speaker fees from Abbott. All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

None
Graphical abstract
Figure 1
Figure 1
The Iatrogenic Atrial Septal Defect Was Measured at 0.5 cm in Diameter

References

    1. Dziadzko V., Dziadzko M., Medina-Inojosa J.R. Causes and mechanisms of isolated mitral regurgitation in the community: clinical context and outcome. Eur Heart J. 2019;40:2194–2202. - PubMed
    1. Nishimura R.A., Otto C.M., Bonow R.O. 2017 AHA/ACC focused update of the 2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2017;135:e1159–e1195. - PubMed
    1. Zoghbi W.A., Adams D., Bonow R.O. Recommendations for noninvasive evaluation of native valvular regurgitation: a report from the American Society of Echocardiography developed in collaboration with the Society for Cardiovascular Magnetic Resonance. J Am Soc Echocardiogr. 2017;30:303–371. - PubMed
    1. Stone G.W., Lindenfeld J., Abraham W.T. Transcatheter mitral-valve repair in patients with heart failure. N Engl J Med. 2018;379:2307–2318. - PubMed
    1. Hart E.A., Zwart K., Teske A.J. Haemodynamic and functional consequences of the iatrogenic atrial septal defect following MitraClip therapy. Neth Heart J. 2017;25:137–142. - PMC - PubMed

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