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Case Reports
. 2020 Jan 23:1:69-71.
doi: 10.1016/j.xjtc.2020.01.010. eCollection 2020 Mar.

Granulocyte-colony stimulating factor- and interleukin-1β-positive cardiac myxoma accompanying neutrophilic dermatosis

Yoichi Ajiro  1 , Hitoshi Nino  2 , Takashi Ueda  3 , Yukihiro Bonkohara  4
Affiliations
Case Reports

Granulocyte-colony stimulating factor- and interleukin-1β-positive cardiac myxoma accompanying neutrophilic dermatosis

Yoichi Ajiro et al. JTCVS Tech. .
No abstract available

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Figures

None
Immunostaining of the cardiac myxoma for G-CSF (left) and IL-1β (right).
Video 1
Video 1
A transesophageal echocardiogram revealed cardiac myxoma during the systemic inspection of afebrile neutrophilic dermatosis. Video available at: https://www.jtcvs.org/article/S2666-2507(20)30027-4/fulltext.
Figure 1
Figure 1
Erythema on the lower limbs (A), and histologic examination of a skin lesion with erythema (B, ×100; C, ×400; D, ×400) showing neutrophil infiltration from epidermis to the pannicule.
Figure 2
Figure 2
Histologic examinations of the cardiac myxoma. The resected cardiac myxoma (A). Hematoxylin staining shows myxoma cells and myxoid stroma (B, ×400). Immunostaining for interleukin-6 (C, ×400), granulocyte colony-stimulating factor (D, ×400), and interleukin-1β (E, ×400) shows brown each cytokine-positive myxoma cells.
See this image and copyright information in PMC

References

    1. Amano J., Kono T., Wada Y., Zhang T., Koide N., Fujimori M., et al. Cardiac myxoma: its origin and tumor characteristics. Ann Thorac Cardiovasc Surg. 2003;9:215–221. - PubMed
    1. Cohen P.R. Sweet's syndrome—a comprehensive review of an acute febrile neutrophilic dermatosis. Orphanet J Rare Dis. 2007;2:34. - PMC - PubMed
    1. Soeparwata R., Poeml P., Schmid C., Neuhof H., Scheld H.H. Interleukin-6 plasma levels and tumor size in cardiac myxoma. J Thorac Cardiovasc Surg. 1996;112:1675–1677. - PubMed
    1. Garlanda C., Dinarello C.A., Mantovani A. The interleukin-1 family: back to the future. Immunity. 2013;39:1003–1018. - PMC - PubMed
    1. Demetri G.D., Zenzie B.W., Rheinwald J.G., Griffin J.D. Expression of colony-stimulating factor genes by normal human mesothelial cells and human malignant mesothelioma cells lines in vitro. Blood. 1989;74:940–946. - PubMed

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