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Multicenter Study
. 2022 Jan 1;47(1):86-87.
doi: 10.1097/RLU.0000000000003830.

Sentinel Lymph Node Biopsy in Prostate Cancer Using the SENSEI® Drop-In Gamma Probe

Jose Maria Abascal Junquera  1 , Antoni Mestre-Fusco  2 , Maarten Ruben Grootendorst  3 , Sergi Vidal-Sicart  1 , Lluis Fumado  1
Affiliations
Multicenter Study

Sentinel Lymph Node Biopsy in Prostate Cancer Using the SENSEI® Drop-In Gamma Probe

Jose Maria Abascal Junquera et al. Clin Nucl Med. .

Abstract

Minimally invasive surgery in the form of laparoscopic and robot-assisted procedures has been widely adopted in the field of prostate cancer. When performing minimally invasive radioguided surgery, conventional rigid laparoscopic gamma probes have limited maneuverability and control due to their form factor, which may hinder detection of radiotracer-avid lesions in anatomically challenging areas. A drop-in gamma probe has been developed to address these limitations. Our group report on the first clinical use of this probe (SENSEI®) as part of an ongoing prospective, international, multicenter clinical trial in primary prostate cancer patients undergoing 99mTc-nanocolloid sentinel lymph node biopsy.

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Conflict of interest statement

Conflicts of interest and sources of funding: This research was supported by funding from Innovate UK (grant no. 105293 and 102840). Lightpoint Medical Ltd (Chesham, United Kingdom) provided material support in the form of the SENSEI drop-in gamma probe system. M.G. is employee of and has equity in Lightpoint Medical Ltd. The remaining authors declare no conflicts of interest.

References

    1. Wit EMK, Acar C, Grivas N, et al. Sentinel node procedure in prostate cancer: a systematic review to assess diagnostic accuracy. Eur Urol . 2017;71:596–605.
    1. Mazzone E, Dell’Oglio P, Grivas N, et al. Diagnostic value, oncological outcomes and safety profile of image-guided surgery technologies during robot-assisted lymph node dissection with sentinel node biopsy for prostate cancer. J Nucl Med . 2021. [Online ahead of print]. doi:10.2967/jnumed.120.259788. - DOI
    1. Valdés Olmos RA, Rietbergen DDD, Rubello D, et al. Sentinel node imaging and radioguided surgery in the era of SPECT/CT and PET/CT: toward new interventional nuclear medicine strategies. Clin Nucl Med . 2020;45:771–777.
    1. van Oosterom MN, Simon H, Mengus L, et al. Revolutionizing (robot-assisted) laparoscopic gamma tracing using a drop-in gamma probe technology. Am J Nucl Med Mol Imaging . 2016;6:1–17.
    1. Dell’Oglio P, Meershoek P, Maurer T, et al. A DROP-IN gamma probe for robot-assisted radioguided surgery of lymph nodes during radical prostatectomy. Eur Urol . 2021;79:124–132.

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