Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2021 Jul 27;117(9):e106-e109.
doi: 10.1093/cvr/cvab212.

NAD+ metabolism and cardiometabolic health: the human evidence

Affiliations
Comment

NAD+ metabolism and cardiometabolic health: the human evidence

Mahmoud Abdellatif et al. Cardiovasc Res. .
No abstract available

Keywords: Ageing; Cardiovascular disease; Diabetes; NMN; NR; Niacin; Nicotinamide; Obesity.

PubMed Disclaimer

Comment on

References

    1. Yoshino J, Baur JA, Imai S-I. NAD+ intermediates: the biology and therapeutic potential of NMN and NR. Cell Metab 2018;27:513–528. - PMC - PubMed
    1. Sciarretta S, Forte M, Castoldi F, Frati G, Versaci F, Sadoshima J, Kroemer G, Maiuri MC. Caloric restriction mimetics for the treatment of cardiovascular diseases. Cardiovasc Res 2021;117:1434–1449. - PubMed
    1. Yoshino M, Yoshino J, Kayser BD, Patti G, Franczyk MP, Mills KF, Sindelar M, Pietka T, Patterson BW, Imai S-I, Klein S. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science 2021;372:1224–1229. - PMC - PubMed
    1. Elhassan YS, Kluckova K, Fletcher RS, Schmidt MS, Garten A, Doig CL, Cartwright DM, Oakey L, Burley CV, Jenkinson N, Wilson M, Lucas SJE, Akerman I, Seabright A, Lai Y-C, Tennant DA, Nightingale P, Wallis GA, Manolopoulos KN, Brenner C, Philp A, Lavery GG. Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures. Cell Rep 2019;28:1717–1728.e6. - PMC - PubMed
    1. Remie CME, Roumans KHM, Moonen MPB, Connell NJ, Havekes B, Mevenkamp J, Lindeboom L, Wit VHW, de Weijer T, van de Aarts SABM, Lutgens E, Schomakers BV, Elfrink HL, Zapata-Pérez R, Houtkooper RH, Auwerx J, Hoeks J, Schrauwen-Hinderling VB, Phielix E, Schrauwen P. Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans. Am J Clin Nutr 2020;112:413–426. - PMC - PubMed

Publication types