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Comment
. 2021 Aug;44(8):595-596.
doi: 10.1016/j.tins.2021.06.008.

Studying dopamine in addiction: the cart should follow the horse

Terry E Robinson  1 , Shaun Y-S Khoo  2 , Carrie R Ferrario  3 , Anne-Noël Samaha  4
Affiliations
Comment

Studying dopamine in addiction: the cart should follow the horse

Terry E Robinson et al. Trends Neurosci. 2021 Aug.
No abstract available

Keywords: addiction; animal models; cocaine self-administration; dopamine; glutamate plasticity.

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References

    1. Lüscher C and Pascoli V (2021) ‘Ups, downs, and sideways’ of dopamine in drug addiction. Trends Neurosci. 44, 593–594 - PubMed
    1. Dong Y et al. (2017) Circuit and synaptic plasticity mechanisms of drug relapse. J. Neurosci 37, 10867–10876 - PMC - PubMed
    1. Wolf ME (2016) Synaptic mechanisms underlying persistent cocaine craving. Nat. Rev. Neurosci 17, 351–365 - PMC - PubMed
    1. Scofield MD et al. (2016) The nucleus accumbens: mechanisms of addiction across drug classes reflect the importance of glutamate homeostasis. Pharmacol. Rev 68, 816–871 - PMC - PubMed
    1. Sarter M and Phillips KB (2018) The neuroscience of cognitive-motivational styles: sign- and goal-trackers as animal models. Behav. Neurosci 132, 1. - PMC - PubMed