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. 2021 Apr 30;28(1):1-5.
doi: 10.4103/meajo.MEAJO_424_20. eCollection 2021 Jan-Mar.

Endophthalmitis Post Pars Plana Vitrectomy Surgery: Incidence, Organisms' Profile, and Management Outcome in a Tertiary Eye Hospital in Saudi Arabia

Bedoor AlBloushi  1   2 , Marco Mura  1 , Rajiv Khandekar  3 , Saleh AlMesfer  4 , Abdulmalik AlYahya  1 , Khaled Alabduljabbar  1 , Shaimaa AlRefaie  1 , Valmore A Semidey  1
Affiliations

Endophthalmitis Post Pars Plana Vitrectomy Surgery: Incidence, Organisms' Profile, and Management Outcome in a Tertiary Eye Hospital in Saudi Arabia

Bedoor AlBloushi et al. Middle East Afr J Ophthalmol. .

Abstract

Purpose: To determine the incidence of endophthalmitis after pars plana vitrectomy (PPV), organisms' profile, and management outcomes at a tertiary eye hospital in a Middle East country.

Methods: In this single-arm cohort study conducted in 2020, medical records of patients who underwent PPV not accompanied by any other intraocular surgery were reviewed; those with a diagnosis of acute endophthalmitis in the immediate postoperative period (within 6 weeks) during the past 6 years were analyzed.

Results: A total of 8153 records of PPV surgeries were reviewed. Five cases had endophthalmitis post-PPV with an incidence of 0.061%. Three (0.037%) had positive cultures, all of them for Staphylococcus epidermidis. The interval between PPV and diagnosis of endophthalmitis ranged from 3 to 25 days (mean, 15.8 days). Final vision after treatment ranged from 20/400 to no light perception, and one eye was eviscerated.

Conclusion: The incidence of endophthalmitis post PPV is low. Despite prompt diagnosis and standard management, visual prognosis seems to be poor. The infective agents for endophthalmitis were commensals from the ocular surface.

Keywords: Endophthalmitis; intraocular infection; pars plana vitrectomy.

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Conflict of interest statement

There are no conflicts of interest.

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References

    1. Eifrig CW, Scott IU, Flynn HW, Jr, Smiddy WE, Newton J. Endophthalmitis after pars plana vitrectomy: Incidence, causative organisms, and visual acuity outcomes. Am J Ophthalmol. 2004;138:799–802. - PubMed
    1. Pershing S, Lum F, Hsu S, Kelly S, Chiang MF, Rich WL, 3rd, et al. Endophthalmitis after cataract surgery in the United States: A report from the intelligent research in sight registry, 2013-2017. Ophthalmology. 2020;127:151–8. - PubMed
    1. Al-Rashaed S, Alsulaiman SM, Alrushood AA, Almasaud J, Arevalo JF. Incidence of endophthalmitis after intravitreal anti-vascular endothelial growth factor: Experience in Saudi Arabia. Middle East Afr J Ophthalmol. 2016;23:60–3. - PMC - PubMed
    1. Khandekar R, Al-Motowa S, Alkatan HM, Karaoui M, Ortiz A. Incidence and determinants of endophthalmitis within 6 months of surgeries over a 2-year period at King Khaled Eye Specialist Hospital, Saudi Arabia: A review. Middle East Afr J Ophthalmol. 2015;22:198–202. - PMC - PubMed
    1. Chen G, Tzekov R, Li W, Jiang F, Mao S, Tong Y. Incidence of endophthalmitis after vitrectomy: A systematic review and meta-analysis. Retina. 2019;39:844–52. - PubMed