OER and RBE for 125I and 192Ir at low dose rate on mammalian cells
- PMID: 3432600
- DOI: 10.1016/s0167-8140(87)80010-5
OER and RBE for 125I and 192Ir at low dose rate on mammalian cells
Abstract
The oxygen enhancement ratio (OER) for 125I and 192Ir as well as the relative biological effectiveness (RBE) at low dose rates (40-80 cGy h-1) were determined for B16 melanoma cells in culture. The OER was found to be 2.1 +/- 0.03 for 125I and 2.7 +/- 0.04 for 192Ir. The RBE for 125I relative to 192Ir was determined as 1.8 +/- 0.03 under aerated conditions and as 2.4 +/- 0.03 under hypoxia.
Similar articles
-
Anisotropy functions for 103Pd, 125I, and 192Ir interstitial brachytherapy sources.Med Phys. 1993 Sep-Oct;20(5):1465-73. doi: 10.1118/1.597110. Med Phys. 1993. PMID: 8289730
-
Microdosimetric evaluation of relative biological effectiveness for 103Pd, 125I, 241Am, and 192Ir brachytherapy sources.Int J Radiat Oncol Biol Phys. 1996 Oct 1;36(3):689-97. doi: 10.1016/s0360-3016(96)00374-4. Int J Radiat Oncol Biol Phys. 1996. PMID: 8948355
-
192Ir or 125I prostate brachytherapy as a boost to external beam radiotherapy in locally advanced prostatic cancer: a dosimetric point of view.Radiother Oncol. 2006 Jan;78(1):47-52. doi: 10.1016/j.radonc.2005.09.002. Epub 2005 Oct 10. Radiother Oncol. 2006. PMID: 16216365
-
Radiation dose dependence of the sensitization by oxygen and oxygen mimic sensitizers.Acta Radiol Oncol. 1985 May-Jun;24(3):209-17. doi: 10.3109/02841868509134389. Acta Radiol Oncol. 1985. PMID: 2994369 Review.
-
[High Dose Rate 192Ir-Microselectron].Ugeskr Laeger. 1990 Oct 1;152(40):2908-10. Ugeskr Laeger. 1990. PMID: 2219528 Review. Danish.
Cited by
-
Improved iodine-125 plaque design in the treatment of choroidal malignant melanoma.Br J Ophthalmol. 1992 Feb;76(2):91-4. doi: 10.1136/bjo.76.2.91. Br J Ophthalmol. 1992. PMID: 1739723 Free PMC article.
-
Dose Rate Effects from the 1950s through to the Era of FLASH.Radiat Res. 2024 Aug 1;202(2):161-176. doi: 10.1667/RADE-24-00024.1. Radiat Res. 2024. PMID: 38954556 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources