OER and RBE for 125I and 192Ir at low dose rate on mammalian cells
- PMID: 3432600
- DOI: 10.1016/s0167-8140(87)80010-5
OER and RBE for 125I and 192Ir at low dose rate on mammalian cells
Abstract
The oxygen enhancement ratio (OER) for 125I and 192Ir as well as the relative biological effectiveness (RBE) at low dose rates (40-80 cGy h-1) were determined for B16 melanoma cells in culture. The OER was found to be 2.1 +/- 0.03 for 125I and 2.7 +/- 0.04 for 192Ir. The RBE for 125I relative to 192Ir was determined as 1.8 +/- 0.03 under aerated conditions and as 2.4 +/- 0.03 under hypoxia.
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