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. 2021 Sep;78(3):647-660.
doi: 10.1161/HYPERTENSIONAHA.121.17177. Epub 2021 Aug 2.

Piezo1-Mediated Mechanotransduction Promotes Cardiac Hypertrophy by Impairing Calcium Homeostasis to Activate Calpain/Calcineurin Signaling

Yuhao Zhang #  1 , Sheng-An Su #  1 , Wudi Li  1 , Yuankun Ma  1 , Jian Shen  1 , Yaping Wang  2 , Yimin Shen  1 , Jian Chen  1 , Yongli Ji  1 , Yao Xie  1 , Hong Ma  1 , Meixiang Xiang  1
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Free article

Piezo1-Mediated Mechanotransduction Promotes Cardiac Hypertrophy by Impairing Calcium Homeostasis to Activate Calpain/Calcineurin Signaling

Yuhao Zhang et al. Hypertension. 2021 Sep.
Free article

Abstract

[Figure: see text].

Keywords: calcineurin; calpain; fibrosis; homeostasis; mechanotransduction.

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