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Multicenter Study
. 2021 Nov 1;274(5):866-873.
doi: 10.1097/SLA.0000000000005116.

Outcomes of Esophagogastric Cancer Surgery During Eight Years of Surgical Auditing by the Dutch Upper Gastrointestinal Cancer Audit (DUCA)

Daan M Voeten  1   2 , Linde A D Busweiler  1   3 , Leonie R van der Werf  1   3 , Bas P L Wijnhoven  4 , Rob H A Verhoeven  5   6 , Johanna W van Sandick  7 , Richard van Hillegersberg  8 , Mark I van Berge Henegouwen  1 ; Dutch Upper Gastrointestinal Cancer Audit (DUCA) Group
Affiliations
Multicenter Study

Outcomes of Esophagogastric Cancer Surgery During Eight Years of Surgical Auditing by the Dutch Upper Gastrointestinal Cancer Audit (DUCA)

Daan M Voeten et al. Ann Surg. .

Abstract

Objective: To evaluate changes in treatment and outcomes of esophagogastric cancer surgery after introduction of the DUCA. In addition, the presence of risk-averse behavior was assessed.

Summary of background data: Clinical auditing is seen as an important quality improvement tool; however, its long-term efficacy remains largely unknown. In addition, critics claim that enhancements result from risk-averse behavior rather than positive effects of auditing.

Methods: DUCA data were used from registration start (1-1-2011) until 31-12-2018. Trends in patient, tumor, hospital and treatment characteristics were univariably assessed. Trends in short-term outcomes were investigated using multilevel multivariable logistic regression. Presence of risk aversion was described by the corrected proportion of patients undergoing surgery, using data from the Netherlands Cancer Registry. To evaluate the impact of centralization on time trends identified, the association between hospital volume and outcomes was investigated.

Results: This study included 6172 patients with esophageal and 3,690 with gastric cancer who underwent surgery. Pathological outcomes (lymph node yield, radicality) improved and futile surgery decreased over the years. In-hospital/30-day mortality decreased for esophagectomy (4.2% to 2.5%) and for gastrectomy (7.1% to 4.3%). Reinterventions, (minor) complications and readmissions increased. Risk aversion appeared absent. Between 2011-2018, annual median hospital volumes increased from 38 to 53 for esophagectomy and from 14 to 29 for gastrectomy. Higher hospital volumes were associated with several improved outcomes measures.

Conclusions: During 8 years of auditing, outcomes improved, with no signs of risk-averse behavior. These improvements occurred in parallel with centralization. Feedback on postoperative complications remains the focus of the DUCA.

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Conflict of interest statement

MIvBH is consultant for Mylan, Johnson & Johnson, Alesi Surgical and Medtronic, and received research grants from Olympus and Stryker. RvH is consultant for Medtronic and proctoring surgeon for Intuitive Surgical Inc. and trains other surgeons in robot-assisted minimally invasive esophagectomy. RHAV received research grants from Roche and Bristol Myers Squibb. For the remaining authors no conflicts of interest were declared. The authors report no conflicts of interest.

References

    1. Busweiler LAD, Wijnhoven BPL, van Berge Henegouwen MI, et al. Early outcomes from the Dutch Upper Gastrointestinal Cancer Audit. Br J Surg 2016; 103:1855–1863.
    1. Busweiler LAD, Schouwenburg MG, van Berge Henegouwen MI, et al. Textbook outcome as a composite measure in oesophagogastric cancer surgery. Br J Surg 2017; 104:742–750.
    1. Voeten DM, van der Werf LR, Wijnhoven BPL, et al. Failure to cure in patients undergoing surgery for esophageal carcinoma: hospital of surgery influences prospects for cure: a nation-wide cohort study. Ann Surg 2020; 272:744–750.
    1. de Neree Tot Babberich MPM, Detering R, Dekker JWT, et al. Achievements in colorectal cancer care during 8 years of auditing in The Netherlands. Eur J Surg Oncol 2018; 44:1361–1370.
    1. Beck N, van Bommel AC, Eddes EH, et al. The Dutch Institute for Clinical Auditing: Achieving Codman's Dream on a Nationwide Basis. Ann Surg 2020; 271:627–631.

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