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. 2021 Jul 17:27:101076.
doi: 10.1016/j.bbrep.2021.101076. eCollection 2021 Sep.

Types of potentials in a mitotic spindle

Yelena Nemchen  1 , Randal Hallford  1 , Preet Sharma  1
Affiliations

Types of potentials in a mitotic spindle

Yelena Nemchen et al. Biochem Biophys Rep. .

Abstract

The dynamics of a mitotic spindle is very important to understand if the functioning of mitosis has to be understood and defined very accurately. There are a number of forces involved in such a process. Despite of the fact that there have been numerous studies done on the functioning of a mitotic spindle, there is still not a very precise understanding of this system and how it behaves. This study aims at understanding and expressing all the possible potentials which might be responsible in a mitotic spindle and its mechanism.

Keywords: Gay–Berne; Lennard-Jones; Mitotic spindle; Potentials.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Mitotic Spindle .
Fig. 2
Fig. 2
Lennard-Jones Potential. rm is the minimum r.
Fig. 3
Fig. 3
Typical molecular structure displaying Lennard-Jones Potential.
Fig. 4
Fig. 4
Typical molecular structure displaying Gay–Berne Potential .
See this image and copyright information in PMC

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References

    1. Dumont S., Mitchison T. Force and length in the mitotic spindle. Curr. Biol. 2009;19:R749. - PMC - PubMed
    1. J. K., M. A. Genes and chromosomes 2: cell division and genetic diversity. Nurs. Times [Online] 2018;114(8):40–47.
    1. Henriques A., Ribeiro D., Pedrosa J., Sarmento B., Silva P., Bousbaa H. Mitosis inhibitors in anticancer therapy: When blocking the exit becomes a solution. Cancer Lett. 2018;440 - PubMed
    1. Doncic A., Ben-Jacob E., Barkai N. Noise resistance in the spindle assembly checkpoint. Mol. Syst. Biol. 2006;2:2006.0027. - PMC - PubMed
    1. Elting M.W., Hueschen C.L., Udy D.B., Dumont S. Force on spindle microtubule minus ends moves chromosomes. J. Cell Biol. 2014;206(2):245–256. - PMC - PubMed

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