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. 2021 Sep 17;65(10):e0106621.
doi: 10.1128/AAC.01066-21. Epub 2021 Aug 2.

Characterization of the First Carbapenem-Resistant Pseudomonas aeruginosa Clinical Isolate Harboring blaSIM-1 from the United States

Catharine Prussing  1 , Theresa Canulla  2   3   4 , Navjot Singh  1 , Patricia McAuley  4   5 , Michael Gosciminski  4   5 , Ewa King  3   4 , Utpala Bandy  4   5 , María-José Machado  6 , Maria Karlsson  6 , Kimberlee A Musser  1 , Richard C Huard  2   3   4 , Elizabeth J Nazarian  1
Affiliations

Characterization of the First Carbapenem-Resistant Pseudomonas aeruginosa Clinical Isolate Harboring blaSIM-1 from the United States

Catharine Prussing et al. Antimicrob Agents Chemother. .
No abstract available

Keywords: Pseudomonas aeruginosa; antibiotic resistance; beta-lactamases; carbapenems; genome analysis; long-read sequencing.

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Figures

FIG 1
FIG 1
Two blaSIM-1 plasmids identified in a Pseudomonas aeruginosa isolate. Colored rings show BLAST comparisons of pPae-WC20-001-01 and pPae-WC20-001-02 to similar plasmids: MH547560.1 from P. aeruginosa (purple), CP046903.1 from P. stutzeri (yellow), and CP007510.1 from P. stutzeri (blue). Coding sequences (CDS) are indicated on the outermost ring of each plasmid in gray, with antimicrobial resistance (AR) genes highlighted in red. Unlabeled CDS encode hypothetical proteins. This figure was created using BLAST Ring Image Generator (BRIG) (29).
See this image and copyright information in PMC

References

    1. Bush K, Bradford PA. 2020. Epidemiology of β-lactamase-producing pathogens. Clin Microbiol Rev 33:e00047-19. 10.1128/CMR.00047-19. - DOI - PMC - PubMed
    1. CDC. 2019. Antibiotic resistance threats in the United States, 2019. U.S. Department of Health and Human Services, CDC, Atlanta, GA.
    1. Lee K, Yum JH, Yong D, Lee HM, Kim HD, Docquier J-D, Rossolini GM, Chong Y. 2005. Novel acquired metallo-β-lactamase gene, blaSIM-1, in a class 1 integron from Acinetobacter baumannii clinical isolates from Korea. Antimicrob Agents Chemother 49:4485–4491. 10.1128/AAC.49.11.4485-4491.2005. - DOI - PMC - PubMed
    1. Kim Y, Roh KH, Lee Y, Chung H-S, Yum JH, Yong D, Lee K, Chong Y. 2013. Clonal change of blaSIM-1-carrying Acinetobacter spp. from 2003 to 2008 in the hospital where it was initially discovered. Microb Drug Resist 19:37–41. 10.1089/mdr.2012.0038. - DOI - PubMed
    1. Lee K, Kim CK, Hong SG, Choi J, Song S, Koh E, Yong D, Jeong SH, Yum JH, Docquier J-D, Rossolini GM, Chong Y. 2010. Characteristics of clinical isolates of Acinetobacter genomospecies 10 carrying two different metallo-β-lactamases. Int J Antimicrob Agents 36:259–263. 10.1016/j.ijantimicag.2010.05.018. - DOI - PubMed

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