Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 Nov-Dec;33(6):344-346.
doi: 10.4103/0970-258X.321144.

Overlapping polyclonal lymphoproliferative disorders

Ramona Bonometti  1 , Mattia Bellan  2 , Daniele Sola  1 , Antonello Gibbin  1 , Francesco Gavelli  3 , Filippo Patrucco  3 , Paolo Spina  4 , Alessandro Gualerzi  1 , Serena Favretto  1 , Luigi Mario Castello  3 , Pier Paolo Sainaghi  2 , Mario Pirisi  2
Affiliations
Case Reports

Overlapping polyclonal lymphoproliferative disorders

Ramona Bonometti et al. Natl Med J India. 2020 Nov-Dec.

Abstract

Multicentric Castleman disease (MCD) is a rare clinical entity characterized by a polyclonal lymphoid proliferation, leading to generalized lymphadenopathy, organomegaly and systemic symptoms. It has been reported in association with either other monoclonal or polyclonal lymphoid disorders, such as POEMS syndrome and immunoglobulin (Ig)G4-related disease. We present a patient showing a variant of MCD, sharing common features with POEMS syndrome and associated with the proliferation of IgG4-producing plasma cells.

PubMed Disclaimer

Conflict of interest statement

None

Publication types