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Comment
. 2021 Aug 2;12(1):4656.
doi: 10.1038/s41467-021-24988-8.

Optical deep-cortex exploration in behaving rhesus macaques

Masanori Matsuzaki  1   2   3 , Teppei Ebina  4
Affiliations
Comment

Optical deep-cortex exploration in behaving rhesus macaques

Masanori Matsuzaki et al. Nat Commun. .

Abstract

Two papers published in June 2021 used a two-photon microscope or one-photon miniature microscope to interrogate the motor cortex in behaving macaque monkeys. The imaging was performed over several months, and the direction of natural arm reaching was decoded from the population activity.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. Two configurations of calcium imaging in the macaque motor cortex.
a Configuration of two-photon imaging by Trautmann et al. It is possible to image the activity of multiple dendrites in the superficial layer of the cortical region under a large cranial window. The same and/or different fields can be imaged across days. The head of the macaque should be fixed. b Configuration of one-photon miniscopic imaging by Bollimunta et al. Chronic calcium imaging of multiple neurons in the same deep-layer field is possible. This is applicable to free-moving macaques.
See this image and copyright information in PMC

Comment on

References

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