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. 2021 Oct;17(5):1934-1936.
doi: 10.1007/s12015-021-10225-8. Epub 2021 Aug 3.

The 9aaTAD Activation Domains in the Yamanaka Transcription Factors Oct4, Sox2, Myc, and Klf4

Martin Piskacek #  1 , Tomas Otasevic  2   3 , Martin Repko  2   3 , Andrea Knight #  4
Affiliations

The 9aaTAD Activation Domains in the Yamanaka Transcription Factors Oct4, Sox2, Myc, and Klf4

Martin Piskacek et al. Stem Cell Rev Rep. 2021 Oct.
No abstract available

Keywords: CBP; KIX; MED15; Sox9; SoxE; Stem cell; iPSCs.

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References

    1. Takahashi, K., & Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell, 126, 663–676. - DOI
    1. Piskacek, M., Havelka, M., Jendruchova, K., Knight, A., & Keegan, L. P. (2019). The evolution of the 9aaTAD domain in Sp2 proteins: Inactivation with valines and intron reservoirs. Cellular and Molecular Life Sciences. https://doi.org/10.1007/s00018-019-03251-w - DOI - PubMed
    1. Sandholzer, J., Hoeth, M., Piskacek, M., Mayer, H., & de Martin, R. (2007). A novel 9-amino-acid transactivation domain in the C-terminal part of Sox18. Biochemical and Biophysical Research Communications, 360, 370–374. - DOI
    1. Piskacek, M., Vasku, A., Hajek, R., & Knight, A. (2015). Shared structural features of the 9aaTAD family in complex with CBP. Molecular BioSystems, 11, 844–851. - DOI
    1. Hofrova, A., Lousa, P., Kubickova, M., Hritz, J., Otasevic, T., Repko, M., Knight, A., & Piskacek, M. (2021). Universal two-point interaction of mediator KIX with 9aaTAD activation domains. Journal of Cellular Biochemistry. https://doi.org/10.1002/jcb.30075 - DOI - PubMed

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