Neuromuscular rehabilitation - what to do?
- PMID: 34343140
- DOI: 10.1097/WCO.0000000000000974
Neuromuscular rehabilitation - what to do?
Abstract
Purpose of review: Rehabilitation for patients with neuromuscular disorders (NMDs) has undisputed health benefits and is potentially therapeutic for targeting impairments, improving quality of life, and enabling activities of daily living. Whilst rehabilitation is commonly prescribed, unequivocal evidence and disease-related guidelines are lacking. This review highlights recent studies of exercise, assistive devices, respiratory management and manual therapy and stretching for patients with NMDs.
Recent findings: Randomised controlled trials of neuromuscular rehabilitation are scant, often underpowered and lack a control group. Recent case studies, clinical trials and cohort studies support rehabilitative therapies such as exercise, respiratory muscle training, assistive devices, and manual therapy and stretching, to provide systemic health benefits, with the possibility to retain or improve function. No evidence of overwork weakness or muscle damage have been reported in exercise trials, and rehabilitative exercise programs in many cases lead to positive psychosocial impacts. Tele-rehab is an emerging area of interest, as a response to the COVID-19 pandemic.
Summary: Robust evidence for the benefits of neuromuscular rehabilitation is lacking, and clinical trial quality can be improved. Tele-rehab is a tantalising development to improve access to neuromuscular rehabilitation in both metropolitan and remote settings during and beyond the COVID-19 pandemic.
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
References
-
- Young P, De Jonghe P, Stögbauer F, et al. Treatment for Charcot-Marie-Tooth disease. Cochrane Library 2008; 2010: DOI: 10.1002/14651858.CD006052.pub2. [Online ahead of print]. - DOI
-
- Burns J, Sman AD, Cornett KM, et al. Safety and efficacy of progressive resistance exercise for Charcot-Marie-Tooth disease in children: a randomised, double-blind, sham-controlled trial. Lancet Child Adolesc Health 2017; 1:106–113.
-
- Sechi A, Zuccarelli L, Grassi B, et al. Exercise training alone or in combination with high-protein diet in patients with late onset Pompe disease: results of a cross over study. Orphanet J Rare Dis 2020; 15:1–11.
-
- Mori L, Signori A, Prada V, et al. Treadmill training in patients affected by Charcot–Marie–Tooth neuropathy: results of a multicenter, prospective, randomized, single-blind, controlled study. Eur J Neurol 2020; 27:280–287.
-
- Taklekar A, Samson A, Palekar T. Effect of structured exercise regimen on quality of life, balance and strength on a patient with Miyoshi Myopathy – a case report. Int J Physiother 2020; 7:186–191.
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