Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Aug 4;23(10):58.
doi: 10.1007/s11883-021-00957-w.

Management of Hypercholesterolemia in Pregnant Women with Atherosclerotic Cardiovascular Disease

Affiliations
Review

Management of Hypercholesterolemia in Pregnant Women with Atherosclerotic Cardiovascular Disease

Aneesha Thobani et al. Curr Atheroscler Rep. .

Abstract

Purpose of review: In this review, we discuss strategies for managing dyslipidemia in pregnant women with ASCVD.

Recent findings: Cardiovascular disease (CVD) is the leading cause of mortality in women as well as the leading cause of pregnancy-related mortality in the USA. It is paramount to screen, identify, counsel, and treat women of childbearing age who have existing atherosclerotic disease to mitigate the risks of complications and mortality. Dyslipidemias, including hypercholesterolemia and hyperlipidemia, can further enhance the risk for future CVD events. Treating hypercholesterolemia during pregnancy is crucial, and this is an opportune time for cross-collaboration of subspecialties in cardiology, obstetrics, and gynecology.

Keywords: Atherosclerosis; Cardiovascular disease; Dyslipidemia; Hypercholesterolemia; Pregnancy; Statin.

PubMed Disclaimer

References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
    1. Benjamin EJ, Virani SS, Callaway CW, et al. Heart disease and stroke statistics-2018 update: a report from the American Heart Association. Circulation. 2018;137(12):e67–492. https://doi.org/10.1161/CIR.0000000000000558 . - DOI - PubMed
    1. Pregnancy Mortality Surveillance System. Updated November 25, 2020. Accessed March 7, 2021, 2021. https://www.cdc.gov/reproductivehealth/maternal-mortality/pregnancy-mort... .
    1. Martin JA, Hamilton BE, Sutton PD, Ventura SJ, Menacker F, Munson ML. Births: final data for 2002. Natl Vital Stat Rep. 2003;52(10):1–113. - PubMed
    1. Matthews TJ, Hamilton BE. Delayed childbearing: more women are having their first child later in life. NCHS Data Brief. 2009;21:1–8.
    1. Lameijer H, Burchill LJ, Baris L, et al. Pregnancy in women with pre-existent ischaemic heart disease: a systematic review with individualised patient data. Heart. 2019;105(11):873–80. https://doi.org/10.1136/heartjnl-2018-314364 . - DOI - PubMed

Substances

LinkOut - more resources