Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2021 Sep 28;326(12):1210-1212.
doi: 10.1001/jama.2021.13443.

Myocarditis and Pericarditis After Vaccination for COVID-19

Affiliations
Multicenter Study

Myocarditis and Pericarditis After Vaccination for COVID-19

George A Diaz et al. JAMA. .

Abstract

This study investigates the incidence of myocarditis and pericarditis emergency department or inpatient hospital encounters before COVID-19 vaccine availability (January 2019–January 2021) and during a COVID-19 vaccination period (February-May 2021) in a large US health care system.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures: Dr Diaz reported receipt of clinical trial research support from Gilead Sciences, Regeneron, Roche, Boehringer Ingelheim, and Edesa Biotech and scientific advisory board membership for Safeology. No other disclosures were reported.

Figures

Figure.
Figure.. Monthly Number of Inpatient and Emergency Department Cases of Myocarditis and Pericarditis at 40 Hospitals in the Western US
A statistical process control c-chart was used for panels A and B, with control limits at ±3 times the standard deviation of the overall count. Orange circles are counts outside the control limits. Solid lines are incidence over the entire time frame; dashed lines are the ±3 sigma (control limits) about the incidence over the entire time frame.

References

    1. Montgomery J, Ryan M, Engler R, et al. . Myocarditis following immunization with mRNA COVID-19 vaccines in members of the US military. JAMA Cardiol. Published online June 29, 2021. doi:10.1001/jamacardio.2021.2833 - DOI - PMC - PubMed
    1. Kim HW, Jenista ER, Wendell DC, et al. . Patients with acute myocarditis following mRNA COVID-19 vaccination. JAMA Cardiol. Published online June 29, 2021. doi:10.1001/jamacardio.2021.2828 - DOI - PMC - PubMed
    1. Bautista García J, Peña Ortega P, Bonilla Fernández JA, et al. . Acute myocarditis after administration of the BNT162b2 vaccine against COVID-19. Rev Esp Cardiol (Engl Ed). Published online April 27, 2021. doi:10.1016/j.recesp.2021.03.009 - DOI - PMC - PubMed
    1. Rosner CM, Genovese L, Tehrani BN, et al. . Myocarditis temporally associated with COVID-19 vaccination. Circulation. Published online June 16, 2021. doi:10.1161/CIRCULATIONAHA.121.055891 - DOI - PMC - PubMed
    1. Su JR, McNeil MM, Welsh KJ, et al. . Myopericarditis after vaccination, Vaccine Adverse Event Reporting System (VAERS), 1990-2018. Vaccine. 2021;39(5):839-845. doi:10.1016/j.vaccine.2020.12.046 - DOI - PubMed

Publication types

MeSH terms