Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Meta-Analysis
. 2021 Jul 1;50(6):788-795.
doi: 10.1097/MPA.0000000000001863.

Endoscopic Versus Laparoscopic Treatment for Pancreatic Pseudocysts: A Systematic Review and Meta-analysis

Wenzhen Hao, Yunli Chen  1 , Yu Jiang  1 , Aiming Yang  2
Affiliations
Meta-Analysis

Endoscopic Versus Laparoscopic Treatment for Pancreatic Pseudocysts: A Systematic Review and Meta-analysis

Wenzhen Hao et al. Pancreas. .

Abstract

Objective: The aim of the study was to evaluate the efficacy and safety of endoscopic treatment for pancreatic pseudocysts (PPCs) compared with laparoscopic treatment.

Methods: The Embase, Medline, Cochrane Library, Web of Science databases, China National Knowledge Infrastructure Chinese citation database, and WANFANG database were systematically searched to identify all comparative trials investigating endoscopic versus laparoscopic treatment for PPC. The main outcome measures included treatment success rate, adverse events, recurrence rate, operation time, intraoperative blood loss, and hospital stay.

Results: Six studies with 301 participants were included. The results suggested that there was no difference in rates of treatment success (odds ratio [OR], 0.90; 95% confidence interval [CI], 0.40-2.01; P = 0.79), adverse events (OR, 0.80, 95% CI, 0.38-1.70; P = 0.57), or recurrence (OR, 0.55, 95% CI, 0.22-1.40; P = 0.21) between endoscopic and laparoscopic treatments. However, the endoscopic group exhibited reduced operation time (weighted mean difference [WMD], -67.11; 95% CI, -77.27 to -56.96; P < 0.001), intraoperative blood loss (WMD, -65.23; 95% CI, -103.38 to -27.08; P < 0.001), and hospital stay (WMD, -2.45; 95% CI, -4.74 to -0.16; P = 0.04).

Conclusions: Endoscopic treatment might be suitable for PPC patients.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

FIGURE 1
FIGURE 1
Flow diagram of the selection process.
FIGURE 2
FIGURE 2
Forest plot showing meta-analysis of treatment success. M-H, Mantel-Haenszel.
FIGURE 3
FIGURE 3
Forest plot showing meta-analysis of adverse events.
FIGURE 4
FIGURE 4
Forest plot showing meta-analysis of operation time.
FIGURE 5
FIGURE 5
Forest plot showing meta-analysis of blood loss.
FIGURE 6
FIGURE 6
Forest plot showing meta-analysis of length of hospital stay.
FIGURE 7
FIGURE 7
Forest plot showing meta-analysis of recurrence.
See this image and copyright information in PMC

References

    1. D'Egidio A, Schein M. Pancreatic pseudocysts: a proposed classification and its management implications. Br J Surg. 1991;78:981–984. - PubMed
    1. Banks PA Bollen TL Dervenis C, et al. . Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013;62:102–111. - PubMed
    1. Lerch MM Stier A Wahnschaffe U, et al. . Pancreatic pseudocysts: observation, endoscopic drainage, or resection? Dtsch Arztebl Int. 2009;106:614–621. - PMC - PubMed
    1. Rosso E Alexakis N Ghaneh P, et al. . Pancreatic pseudocyst in chronic pancreatitis: endoscopic and surgical treatment. Dig Surg. 2003;20:397–406. - PubMed
    1. Gouyon B Lévy P Ruszniewski P, et al. . Predictive factors in the outcome of pseudocysts complicating alcoholic chronic pancreatitis. Gut. 1997;41:821–825. - PMC - PubMed

MeSH terms