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Randomized Controlled Trial
. 2021;30(6):522-526.
doi: 10.1159/000517976. Epub 2021 Jun 23.

Nasal Polyposis and Its Association with Cardiac Functions

Sapna Dhiman  1 , Abhishek Dhiman  2 , Ramesh K Azad  1 , Prakash C Negi  3 , Bhushan Lal  1 , Jagdeep S Thakur  1
Affiliations
Randomized Controlled Trial

Nasal Polyposis and Its Association with Cardiac Functions

Sapna Dhiman et al. Med Princ Pract. 2021.

Abstract

Objective: The aim of the study was to ascertain the effect of nasal polyposis on cardiac functions.

Material and methods: A prospective randomized interventional open-label endpoint-controlled study was conducted in an academic tertiary care hospital. Thirty-one patients with chronic rhinosinusitis with nasal polyposis were enrolled and administered fluticasone furoate nasal spray for 3 weeks before randomly segregation into surgical or medical group. The treatment continued for 3 months in both groups. The SNOT-22 (Sino-Nasal Outcome Test-22) score, polyp grade, and right ventricular and pulmonary arterial functions were recorded in both groups before and after 3 months of the intervention.

Results: Both groups had significant improvement in SNOT-22 scores after 3 months of intervention. Both groups showed improvement in cardiac functions, but statistical significance was found only in subjects who underwent surgery.

Conclusion: Nasal polyp affects cardiac functions, and this needs further evaluation and research through studies on large samples.

Keywords: Nasal polyps; Right ventricular function; Sinusitis; Surgery.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

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