Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Meta-Analysis
. 2021 Aug 4;21(1):755.
doi: 10.1186/s12879-021-06441-9.

Prevalence of strongyloidiasis in Peru: systematic review and meta-analysis

Sonia Ortiz-Martínez #  1 , José-Manuel Ramos-Rincón #  2   3 , María-Esteyner Vásquez-Chasnamote  4 , Olga-Nohelia Gamboa-Paredes  5 , Katty-Madeleine Arista-Flores  5 , Luis-Alfredo Espinoza-Venegas  6 , Eva de-Miguel-Balsa  7   8 , Viviana-Vanessa Pinedo-Cancino  9 , Miguel Górgolas-Hernández-Mora #  10   11 , Martín Casapía-Morales #  6   12   13
Affiliations
Meta-Analysis

Prevalence of strongyloidiasis in Peru: systematic review and meta-analysis

Sonia Ortiz-Martínez et al. BMC Infect Dis. .

Abstract

Background: Strongyloidiasis is a disease of great public health significance, caused by the parasitic nematodes Strongyloides stercoralis, Strongyloides fuelleborni, and Strongyloides fuelleborni subsp. kellyi. This systematic review and meta-analysis aimed to assess the prevalence of Strongyloides stercoralis infection in Peru.

Methods: The review was based on a literature search in PubMed, SciELO and Google Scholar using the key words or root words "strongyl*" AND "Peru" on 15 July 2020. Eligible studies were published from 1 January 1981 to 15 July 2020 and written in English, Spanish, Italian, or French.

Results: We included 21 papers in the analysis. Studies were heterogeneous in terms of study population and diagnostic methods (e.g. Baermann technique, agar, Dancescu or charcoal cultures, serology, string capsule). Prevalence of S. stercoralis ranged from 0.3 to 45%. The pooled proportion of Strongyloides in the general population was 7.34% (95% CI 4.97 to 10.13%). Half the studies were designed to detect parasites in general. In studies designed to detect S. stercoralis, the most widely used diagnostic method was the Baermann technique.

Conclusion: Prevalence of S. stercoralis in Peru was high but varied by geographic area, techniques for stool examination, and participant characteristics.

Keywords: Peru; Prevalence; Serology; Seroprevalence; Strongyloides stercoralis.

PubMed Disclaimer

Conflict of interest statement

The authors have declared no conflict of interest.

Figures

Fig. 1
Fig. 1
Flow chart for study selection
Fig. 2
Fig. 2
Forest plot of pooled prevalence of Strongyloides infection in general population
Fig. 3
Fig. 3
Forest plot of pooled prevalence of Strongyloides infection in children
Fig. 4
Fig. 4
Forest plot of pooled prevalence of Strongyloides infection in adults
See this image and copyright information in PMC

References

    1. Krolewiecki A, Nutman TB. Strongyloidiasis: a neglected tropical disease. Infect Dis Clin N Am. 2019;33(1):135–151. doi: 10.1016/j.idc.2018.10.006. - DOI - PMC - PubMed
    1. Schär F, Trostdorf U, Giardina F, Khieu V, Muth S, Marti H, et al. Strongyloides stercoralis: global distribution and risk factors. PLoS Negl Trop Dis. 2013;7(7):1–17. doi: 10.1371/journal.pntd.0002288. - DOI - PMC - PubMed
    1. Bisoffi Z, Buonfrate D, Montresor A, Requena-Méndez A, Muñoz J, Krolewiecki AJ, et al. Strongyloides stercoralis: a Plea for action. PLoS Negl Trop Dis. 2013;7(5):7–10. doi: 10.1371/journal.pntd.0002214. - DOI - PMC - PubMed
    1. Buonfrate D, Bisanzio D, Giorli G, Odermatt P, Fürst T, Greenaway C, French M, Reithinger R, Gobbi F, Montresor A, Bisoffi Z. The global prevalence of Strongyloides stercoralis infection. Pathogens. 2020;9(6):468. doi: 10.3390/pathogens9060468. - DOI - PMC - PubMed
    1. Van De N, Minh PN, Van Duyet L, Mas-Coma S. Strongyloidiasis in northern Vietnam: epidemiology, clinical characteristics and molecular diagnosis of the causal agent. Parasites Vectors. 2019;12(1):1–12. doi: 10.1186/s13071-018-3256-z. - DOI - PMC - PubMed

LinkOut - more resources