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Comment
. 2021 Aug 4;7(32):eabk1668.
doi: 10.1126/sciadv.abk1668. Print 2021 Aug.

Controlling inflammation in the elderly with BCG vaccination

Affiliations
Comment

Controlling inflammation in the elderly with BCG vaccination

Valerie A C M Koeken. Sci Adv. .

Abstract

The tuberculosis vaccine BCG may protect against inflammation in the elderly as well as offer an option for protection from SARS-CoV-2 in developing countries.

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Figures

Fig. 1
Fig. 1. In the elderly, BCG vaccination leads to a decrease in circulating inflammatory proteins and an increase in innate immune responses upon stimulation.
These results provide an opportunity for utilizing BCG as a tool to counteract inflammaging, a chronic low-grade inflammation, as well as immune senescence, the gradual deterioration of the immune system, which develop with advanced age. Credit: Ashley Mastin/Science Advances.

Comment on

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