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Case Reports
. 2021 Aug;12(4):127-131.
doi: 10.14740/wjon1375. Epub 2021 Jul 10.

Metastatic Gastric Cancer to the Colon

Eric Omar Then  1   2 , Tyler Grantham  3 , Xheni Deda  2 , Rajarajeshwari Ramachandran  1 , Vinaya Gaduputi  2
Affiliations
Case Reports

Metastatic Gastric Cancer to the Colon

Eric Omar Then et al. World J Oncol. 2021 Aug.

Abstract

Gastric cancer is one of the most common and deadly cancers worldwide, especially amongst older males. Current data suggest gastric cancer is the fifth most common neoplasm and the third most deadly cancer, with an estimated 783,000 deaths in 2018. Risk factors associated with the development of gastric cancer include obesity, gastroesophageal reflux disease, Helicobacter pylori infection, and low socioeconomic status. Diagnosis of gastric cancer can be accomplished by endoscopy, which allows the clinician to obtain a biopsy specimen. Endoscopic ultrasound is also an important modality that is helpful in assessing tumor invasion. The most common sites of metastatic gastric cancer in descending order are the liver, peritoneum, lung and bone. Rarely will gastric cancer metastasize to the colon. Here we present a rare case of colonic metastasis of a primary gastric adenocarcinoma.

Keywords: Colon; Gastric cancer; Metastasis.

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Conflict of interest statement

The case report was presented in the form of an abstract (poster) in the American College of Gastroenterology Conference in San Antonio, TX (October 2019), USA.

Figures

Figure 1
Figure 1
CT abdomen showing a mid-transverse colon mass measuring 30 × 44 mm resulting in proximal colonic obstruction (red arrows). (a) Axial view. (b) Coronal view. CT: computed tomography.
Figure 2
Figure 2
Colon mass biopsy specimen showing tumor cells infiltrating the muscularis propria and submucosa. (a) × 10 magnification view. (b) × 40 magnification view.
Figure 3
Figure 3
Tumor cells staining positively to CK7 and negative for CK20 and CDX2 (not shown), consistent with gastric origin. CK: cytokeratin.
See this image and copyright information in PMC

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